Results 51 to 60 of about 9,794 (276)

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

Milk Donation Awareness of Parents, Health Workers and Lactation Consultants: Survey Findings

open access: yesВопросы современной педиатрии, 2016
Background. Today, in Russia there is no practice of using donor milk in hospitals, while abroad it is a common technique of caring for premature and low-weight infants.Objective: Our aim was to study the milk donation awareness of parents of children ...
Olga L. Lukoyanova   +13 more
doaj   +1 more source

Donor breast milk banking [PDF]

open access: yesBMJ, 2006
Mother's milk is recommended for all babies, but mothers of preterm babies and other babies in intensive care are often unable or too ill to provide enough milk for their baby's needs. Mother's milk protects against infection and enhances neurocognitive development; it may also improve enteral tolerance and long term metabolic health as well as reduce ...
openaire   +2 more sources

Every Drop Counts—The Current Methods for Determining the Quality of Human Milk

open access: yesProceedings
Background and objectives: Human milk is the golden standard in infant nutrition. A very important segment of nutritional support for premature children is milk banks.
Nikoleta Lugonja   +5 more
doaj   +1 more source

Postpartum women’s views on human milk banking in a city in Southeast China: a cross-sectional survey

open access: yesInternational Breastfeeding Journal, 2022
Background Donor human milk is the best alternative for preterm infants when their mother’s own milk is insufficient or unavailable. The development of human milk banks in China started late, and in most of these banks, the amount of donor human milk is ...
Haixia Tu   +5 more
doaj   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang   +19 more
wiley   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

Human Milk Banks and the Rules for Milk Siblings (Raḍā’)

open access: yes, 2022
Human milk is an excellent diet for newborns because it supplies important nourishment while protecting them from sickness. A milk tie, or milk kinship, is formed when milk from a woman other than the child\u27s mother is consumed.
Niazi, Dr.Samia Maqbool   +1 more
core  

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li   +4 more
wiley   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen   +18 more
wiley   +1 more source

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