Results 131 to 140 of about 242,756 (263)

Effects of SIRT7 Inhibition on Milk Fat Synthesis and Fatty Acid Composition in Dairy Goat Mammary Epithelial Cells. [PDF]

Animals (Basel)
Li J, Li Z, Han M, Zhao M, Li Z, Shi H, Han H, Liu K, Liu X, Quan K.   +9 more
europepmc   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Milk Fat Globule Membrane: Structural Organization, Bioactive Constituents, and Therapeutic Applications. [PDF]

Foods
Lv H, Sun M, Mi M, Sun S, Zhao Y, Du X, Zhang X, Zhu M, Wang Y, Khan MZ, Wang C, Li M.   +11 more
europepmc   +1 more source

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu, Jiaheng Lin, Yifei Zhu, Ying Liu, Guoren Zhou   +4 more
wiley   +1 more source

Construction of the ceRNA Regulatory Network Associated with Milk Fat Metabolism. [PDF]

Animals (Basel)
Feng X, Cheng S, Lu Z, Chen X, Mu T, Wang C, Gu Y, Li Y, Chen X, Zheng J, Guo P.   +10 more
europepmc   +1 more source

Studies in the secretion of milk fat [PDF]

Biochemical Journal, 1938
J A, Smith, N N, Dastur
openaire   +4 more sources

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

Sodium Bicarbonate Can Increase Milk Fat Concentration in Lactating Ewes Fed Ryegrass Herbage Rich in Water-Soluble Carbohydrates. [PDF]

Animals (Basel)
Porcu MA, Ledda A, Carta S, Francesconi AHD, Cannas A.   +4 more
europepmc   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Methods for Preserving Human Milk Cellular and Milk Fat Globule RNA. [PDF]

J Mammary Gland Biol Neoplasia
Li Z, Fischbein N, Jin F, Mui W, Co R, Ginsburg AS, Laleau V, Nyquist S, O'Brien KO, Ahituv N, Flaherman V, Golan Y.   +11 more
europepmc   +1 more source