Results 151 to 160 of about 128,751 (314)

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Impacts of hoof disorders on milk yield in cattle: a systematic review with meta-analysis. [PDF]

Trop Anim Health Prod
Freitas JLDP, Costa PHC, Soares ALESS, Freitas LMD, Pinto LFB.   +4 more
europepmc   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Association study of the <i>CSN2</i> gene with milk yield in the Sapera goat. [PDF]

J Adv Vet Anim Res
Asmarasari SA, Siregar GAW, Saputra F, Praharani L, Muttaqin Z, Kusumaningrum DA, Azizah N, Puastuti W, Yulistiani D, Rusdiana S, Anggraeni A, Suyatno S, Prabowo TA, Pratiwi N, Hidayat C.   +14 more
europepmc   +1 more source

Genetic studies on gestation period and it’s influence on first lactation milk yield in Jersey (J) × Red Sindhi (RS) crosses [PDF]

, 2019
Kuchekar Hd, Bhosale Tr, GR Antre, Singh Rp   +3 more
openalex  

B4GALNT4‐Mediated Glycosylation of PDK1 Activates the PI3K‐AKT Signaling Pathway to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
This study identifies B4GALNT4 as a key driver of prostate cancer (PCa). It shows that B4GALNT4 glycosylates PDK1 protein at the N531 site, which stabilizes the PDK1 and constitutively activates the PI3K‐AKT pathway. This mechanism promotes tumor cell proliferation, migration, and invasion. The findings establish the B4GALNT4‐PDK1 glycosylation axis as
Shaoqin Jiang, Mengqiang Li, Qingfu Su, Ruiling Dou, Shaoshan Lin, Jili Zhang, Xiaochen Sun, Haolan Yu, Wei Bao, Min Qu, Yan Wang, Chenghua Yang, Xu Gao   +12 more
wiley   +1 more source

Heterogeneity of Variances in Milk Yield in Murrah Buffaloes. [PDF]

Animals (Basel)
Camargo Júnior RNC, de Araújo CV, Marques JRF, Bonin Gomes MN, da Silva WC, Belo TS, Sousa CEL, da Silva ÉBR, Marques LC, da Silva MM, Picanço MLR, Lourenço-Júnior JB, Santos AM, de Oliveira AS, Cara JRF, Silva AGME, Silva AGME.   +16 more
europepmc   +1 more source

The nonlinear effect of somatic cell count on milk composition, coagulation properties, curd firmness modeling, cheese yield, and curd nutrient recovery [PDF]

, 2016
Tania Bobbo, Claudio Cipolat‐Gotet, Giovanni Bittante, Alessio Cecchinato   +3 more
openalex   +1 more source

Comparison of Several Forms of Equations for Predicting Cheddar Cheese Yield from Milk Composition

, 2021
Craig A. Moore
openalex   +2 more sources

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Advanced Science, EarlyView.
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih, Nicolas L.A. Dumaire, Clémence Gieré, Erin Vest, Haya Alkhateeb, Christian P. Moritz, Yannick Tholance, Jean‐Philippe Camdessanché, Jean‐Christophe Antoine, Jérôme Honnorat, Jafar Kafaie, Liberty François‐Moutal, Aubin Moutal   +12 more
wiley   +1 more source