Results 231 to 240 of about 2,116,629 (302)

Association study of the <i>CSN2</i> gene with milk yield in the Sapera goat. [PDF]

J Adv Vet Anim Res
Asmarasari SA, Siregar GAW, Saputra F, Praharani L, Muttaqin Z, Kusumaningrum DA, Azizah N, Puastuti W, Yulistiani D, Rusdiana S, Anggraeni A, Suyatno S, Prabowo TA, Pratiwi N, Hidayat C.   +14 more
europepmc   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Perturbations in Dairy Cows: Impact of Heat Stress, Lameness, and Mastitis on Milk Yield and Feeding Behavior. [PDF]

Animals (Basel)
Cabbia A, Braidot M, Florit E, Corazzin M, Romanzin A.   +4 more
europepmc   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Quantifying milk yield-dependent aflatoxin B1-to-M1 transfer in dairy cows: a Bayesian consensus toxicokinetic model. [PDF]

Arch Toxicol
Moenning JL, Numata J.
europepmc   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

Advanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren, Qian Yue, Ning Gao, Qiu‐Lian Hao, Yan Huo, Chuchu Li, Xinyue Leng, Lu‐Lu Sun, Maggie Pui Man Hoi, Hai‐Hao Han, Mingliang Ma, Xu‐Wen Li   +11 more
wiley   +1 more source

Differential responses to soybean meal and canola meal based diet protein levels in mid-lactation dairy cows with different milk yield and parity. [PDF]

Vet Anim Sci
Yang ZQ, Su YJ, Cao BB, Zhang XK, Wu TY, Gu FF, Gong Y, Wang WD, Wang FX, Zhang RH, Zhang XY, Zhou Q, Wei ZH.   +12 more
europepmc   +1 more source

m5C Reader ALYREF Promotes the Progression of Endometrial Cancer by Activating the XRCC6‐Mediated Wnt/β‐catenin Signaling Pathway

Advanced Science, EarlyView.
This study identifies ALYREF as an oncogenic m5C reader in endometrial cancer. ALYREF recognizes NSUN2‐mediated m5C modification on XRCC6 mRNA to enhance transcript stability and increase XRCC6 expression. Elevated XRCC6 activates Wnt/β‐catenin signaling, resulting in accelerated tumor cell proliferation, migration, invasion, and xenograft tumor growth.
Linlin Hao, Jian Zhang, Qi Qian, Min Jiang, Yu Liu, Yan Geng, Nan Cui, Qi Guo, Jie Guo   +8 more
wiley   +1 more source

Partial Substitution of Soybean Meal with a Yeast-Fermented Vinasse Protein Source: Effects on Milk Yield, Composition, and Serum Biochemistry in Crossbred Dairy Cows. [PDF]

Metabolites
Akdag A.
europepmc   +1 more source