Results 251 to 260 of about 464,180 (314)

Milk yield prediction in Friesian cows using linear and flexible discriminant analysis under assumptions violations. [PDF]

BMC Vet Res
Moawed SA, Mahrous E, Elaswad A, Gouda HF, Fathy A.   +4 more
europepmc   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Meta-analysis of the effects of the dietary inclusion of brewers grains on feed intake, milk yield, and feed efficiency of lactating dairy cows. [PDF]

JDS Commun
Chelkapally SC, Terrill TH, Ogunade IM, Estrada-Reyes ZM, Pech-Cervantes AA.   +4 more
europepmc   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Milking Reactivity in Primiparous Saanen Goats During Early Lactation: Effects on Milk Yield, Milk Quality and Plasma Cortisol Concentration. [PDF]

Animals (Basel)
Andrioli M, Grajales-Cedeño JK, Sant'Anna AC, Negrão JA, Paranhos da Costa MJR.   +4 more
europepmc   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Understanding the dynamics of mastitis in milk yield: Decoding onset and recovery patterns in response to mastitis occurrence. [PDF]

JDS Commun
Sguizzato ALL, da Silva TE, Chagas JCC, Argüelo AM, Gonçalves NM, Marcondes MI.   +5 more
europepmc   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Genome-Wide Association Study for Test-Day Milk Yield, Proteins, and Composition Traits of Crossbred Dairy Cattle in Ethiopia. [PDF]

Int J Genomics
Rekik B, Mestawet T, Girma A, Seid M, Besufekad J, Meseret S.   +5 more
europepmc   +1 more source

Transforming the tradition of discrete milk yield correction factors: A continuous 1-step DeLorenzo-Wiggans method. [PDF]

JDS Commun
Wu XL, Caputo MJ, Wiggans GR, Norman HD, Miles AM, Van Tassell CP, Baldwin RL, Schutz MM, Burchard J, Dürr J.   +9 more
europepmc   +1 more source