Results 71 to 80 of about 128,751 (314)
This study was conducted to determine the effect of hemoglobin(Hb) type, breed, sex and season of calving on milk yield characteristics of Bunaji and Friesian x Bunaji cows. The experimental animals consisted of 24 Bunaji and 26 (F1) cross bred (Friesian
C Alphonsus +3 more
doaj
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Fungal mycelia grown into biodegradable scaffolds and infused with titania nanoparticles show enhanced ultraviolet shielding, thermal protection, and surface nonwettability. Properties were tuned by drying methods, revealing structure–function relationships.
Juwon S. Afolayan +2 more
wiley +1 more source
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu +14 more
wiley +1 more source
Genetic parameters of 305 days and monthly test-day milk yields in Murrah buffaloes
The present investigation was carried out using first lactation 9,071 monthly test-day milk yield records of 965 Murrah buffaloes that calved from 1977 to 2012 sired by 98 bulls maintained at ICAR-National Dairy Research Institute, Karnal.
MANVENDRA SINGH +6 more
doaj +1 more source
Variation in Lactation Yield of Milk Constituents
Abstract The lactation production of milk, milk fat, solids-not-fat (SNF), and total solids from cows of six breeds in seven Midwest states was used to investigate gross environmental effects on these traits and to consider correlated responses due to selection for a single trait.
R P, Blanchard, A E, Freeman, P W, Spike
openaire +2 more sources

