Results 81 to 90 of about 464,180 (314)

Studies on restricted suckling in dual purpose and dairy breed cattle in Mexico [PDF]

, 2005
The aim of this thesis was to investigate the effects of rearing calves by restricted suckling (RS) compared to artificial rearing (AR) in dual purpose and dairy breed cattle in Mexico, milked once or three times a day, respectively.
Fröberg, Sofie
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Genetic parameter estimation to milk yield and fat and protein yield deviated from 3% of concentration in milk, in dairy herds of southern Chile

Austral Journal of Veterinary Sciences, 2017
Chilean milk processing industry is providing clear signs to milk farmers regarding the significant importance of milk solids within raw milk payment schemes.
Héctor Uribe, Humberto González, Carlos Gatica   +2 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Genetic parameters for milk mineral content and acidity predicted by mid-infrared spectroscopy in Holstein–Friesian cows [PDF]

, 2015
peer-reviewedThis article was first published in animal, Volume 9, Issue 05, May 2015, pp 775-780 © The Animal Consortium 2015The aim of the present study was to estimate genetic parameters for calcium (Ca), phosphorus (P) and titratable acidity (TA) in ...
Berry, Donagh, Cassandro, M., de Marchi, M., McParland, Sinead, Penasa, M., Toffanin, V.   +5 more
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

The differentiated milk recording when milking into the milk line

Аграрная наука Евро-Северо-Востока, 2019
The article is devoted to theoretical and experimental substantiation of technical capability of the differentiated recording of milk when milking into the milk line.
A. A. Rylov, P. A. Savinykh, V. N. Shulyatyev   +2 more
doaj   +1 more source

Detection of abnormal recordings in Irish milk recorded data [PDF]

, 2007
peer-reviewedThe objective of this study was to detect abnormal recordings of milk yield, fat concentration and protein concentration in Irish milk-recorded data.
Buckley, Frank, Guinee, Timothy P., Killen, L., Quinn, N.   +3 more
core  

Investigations on Milk Flow and Milk Yield from Teats with Milk Flow Disorders

Journal of Dairy Science, 2002
The objective of this study was to investigate peak milk flow, average milk flow, and milk yield in teats with milk flow disorders. A total of 100 hard milking teats were studied in 97 cows. Teats with milk flow disorders were examined endoscopically.
Julia, Ouerengässer, Thomas, Geishauser, Klaus, Querengässer, Rupert, Bruckmaier, Klaus, Fehlings   +4 more
openaire   +2 more sources