Results 231 to 240 of about 43,519 (315)

Atacama Large Aperture Submillimeter Telescope (AtLAST) science: Our Galaxy. [PDF]

Open Res Eur
Klaassen P, Traficante A, Beltrán M, Pattle K, Booth M, Lovell J, Marshall J, Hacar A, Gaches B, Bot C, Peretto N, Stanke T, Arzoumanian D, Duarte Cabral A, Duchêne G, Eden D, Hales A, Kauffmann J, Luppe P, Marino S, Redaelli E, Rigby A, Sánchez-Monge Á, Schisano E, Semenov D, Spezzano S, Thompson M, Wyrowski F, Cicone C, Mroczkowski T, Cordiner M, Di Mascolo L, Johnstone D, van Kampen E, Lee M, Liu D, Maccarone T, Saintonge A, Smith M, Thelen A, Wedemeyer S.   +40 more
europepmc   +1 more source

Coactosin‐Like Protein Reduces Prostaglandin D2 Production in Alveolar Macrophages and Alleviates Allergic Airway Inflammation

Advanced Science, EarlyView.
Coactosin‐like protein inhibits prostaglandin D₂ (PGD2) secretion by modulating alveolar macrophage polarization, thereby suppressing activation of the PGD2 receptor CRTH2 in Th2‐associated immune cells and alleviating allergic airway inflammation.
Li‐Long Pan, Zhengnan Ren, Binbin Li, Wenjie Liang, Yang Luo, Qin Yang, He Liu, Xiaoliang Dong, Haizhi Tian, Huimin Zou, Bengt Samuelsson, Olof Rådmark, Jia Sun   +12 more
wiley   +1 more source

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy

Advanced Science, EarlyView.
This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang, Wengui Lu, Zhifei Cheng, Luyao Wang, Zhenzhen Jiang, Yike Yue, Pengyu Jiang, Zehua Xia, Lei He, Fengying Wang, Limin Wu, Qi Wang, Hui Han   +12 more
wiley   +1 more source

Isolation of Lactic Acid Bacteria from Naturally Ensiled <i>Rosa roxburghii</i> Tratt Pomace and Evaluation of Their Ensiling Potential and Antioxidant Properties. [PDF]

Foods
Pan X, Zhang Y, Yue N, Yu K, Zhou L, Ge L, Chen F, Yang J, Li Q, Deng T, Yang X.   +10 more
europepmc   +1 more source

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu, Shaobo Kang, Na Lin, Wenqi Zhang, Shiwen Wang, Yuqing Ren, Xiaofan Ding, Jianxiu Yu, Ruiyu Xie   +8 more
wiley   +1 more source

A probable Keplerian disk feeding an optically revealed massive young star. [PDF]

Nature
McLeod AF, Klaassen PD, Reiter M, Henshaw J, Kuiper R, Ginsburg A.   +5 more
europepmc   +1 more source

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

An investigation into mental illness and its comorbidities from the perspective of supervenience physicalism. [PDF]

Philos Ethics Humanit Med
Yang P, Zhang X, Song H, Zhang X.
europepmc   +1 more source

Analysis of regularity/chaoticity of the Globular ckusters dynamics in the central region of the Milky Way

A.T. Bajkova, A.A. Smirnov, V.V. Bobylev
openalex   +1 more source

Anti‐Inflammatory Mechanisms of Selenium Nanosheets in Ulcerative Colitis: Protein Corona, GP130 Interaction, and Transcriptomic Profile

Advanced Science, EarlyView.
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen, Li Gong, Wei Yang, Jiaqi Luo, Zhen Jin, Youzhi Tang   +5 more
wiley   +1 more source