Results 141 to 150 of about 90,260 (324)

Integrin β4‐Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

Advanced Healthcare Materials, EarlyView.
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng, Aijun Liang, Maximus CF Yeung, Sze Keong Tey, Kam‐Leung Siu, Sin‐Yee Fung, Dong‐Yan Jin, Judy Wai Ping Yam   +7 more
wiley   +1 more source

Measurement of Dependence of Microlensing Planet Frequency on the Host Star Mass and Galactocentric Distance by Using a Galactic Model

The Astrophysical Journal
We measure the dependence of planet frequency on host star mass, M _L , and distance from the Galactic center, R _L , using a sample of planets discovered by gravitational microlensing.
Kansuke Nunota, Naoki Koshimoto, Daisuke Suzuki, Takahiro Sumi, David P. Bennett, Aparna Bhattacharya, Yuki Hirao, Sean K. Terry, Aikaterini Vandorou   +8 more
doaj   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Galaxias Enanas del Grupo Local

Momento, 2009
The satellite galaxies of the Milky Way are very important both for the studies of the formation and evolution of galaxies and for the research on the dark matter problem. In the present review paper some structural properties of the Local Group, as well
A Casallas Lagos, D J Cubillos, R A Casas Miranda   +2 more
doaj  

Rising from the Ashes. II. The Bar-driven Abundance Bimodality of the Milky Way

The Astrophysical Journal
The Milky Way hosts at least two modes in its present-day distribution of Fe and α -elements. The exact cause of this bimodality is disputed, but one class of explanations involves the merger between the Milky Way and a relatively massive satellite (Gaia-
Angus Beane, James W. Johnson, Vadim A. Semenov, Lars Hernquist, Vedant Chandra, Charlie Conroy   +5 more
doaj   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

Advanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis, Subhajit Dutta, Saqib Kamal, Sergio Gómez‐Graña, Isabel Pastoriza‐Santos, Stefan Wuttke, Lakshminarayana Polavarapu   +6 more
wiley   +1 more source

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

Advanced Materials, EarlyView.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal, Sandra Clara‐Trujillo, Elena Lucena‐Sánchez, Francisco J. Hicke, Andrea Escudero, Sandra Pradana‐López, Nelia Jiménez‐Alduan, Paula Díez, Alba García‐Fernández, Ramón Martínez‐Máñez   +9 more
wiley   +1 more source

Bar formation in the Milky Way type galaxies

, 2017
8 pages, 5 ...
Polyachenko, E. V., Berczik, P., Just, A.   +2 more
openaire   +2 more sources

Density, Alternative Determinant of Star Formation Efficiency of the Milky Way GMCs: Core Reason for Low Star Formation Efficiency [PDF]

, 2021
Okezuonu Patrick Chinedu, Ogwo Jemima Ngozi   +1 more
openalex   +1 more source

An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide

Advanced Materials, EarlyView.
Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon, Charles T. Osborne, Ke Wang, Rachel E. Detwiler, Konrad Meister, Jessica R. Kramer   +5 more
wiley   +1 more source