Results 191 to 200 of about 8,242 (260)

Pixelation of perovskite quantum wire thin films with 0.18-μm features and 63,500-ppi pixel density. [PDF]

Sci Adv
Zhang Q, Sun X, Chen G, Ma Z, Zhang D, Zhou Y, Qiu X, Ren B, Ding Y, Poddar S, Tang W, Lv H, Mo X, Fan Z.   +13 more
europepmc   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Resolved Mass Assembly and Star Formation in Milky Way Progenitors since z = 5 from JWST/CANUCS: From Clumps and Mergers to Well-ordered Disks

Vivian Yun Yan Tan, Adam Muzzin, Ghassan T. E. Sarrouh, Jacqueline Antwi-Danso, Visal Sok, Naadiyah Jagga, Gregor Rihtaršič, Westley Brown, Roberto Abraham, Yoshihisa Asada, G. Desprez, Kartheik G. Iyer, Nicholas S. Martis, Rosa M. Mérida, Lamiya Mowla, Gaël Noirot, Kiyoaki Christopher Omori, Marcin Sawicki, Roberta Tripodi, Chris J. Willott   +19 more
openalex   +1 more source

Clinical translation of TLR agonist-modified silicified cancer cell therapy supported by humanized mouse models. [PDF]

Mol Ther Oncol
Steinkamp MP, Burke D, Morrison M, Lagutina I, Fitzpatrick L, Serda RE.   +5 more
europepmc   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Study of Aroma Characteristics and Establishment of Flavor Molecular Labels in Fermented Milks from Different Fermentation Strains. [PDF]

Foods
Xu R, Tang L, Gao X, Han X, Liu C, Song H.   +5 more
europepmc   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Status of Electromagnetically Accelerating Universe. [PDF]

Entropy (Basel)
Frampton PH.
europepmc   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Development of Oleic Acid Composite Vesicles as a Topical Delivery System: An Evaluation of Stability, Skin Permeability, and Antioxidant and Antibacterial Activities. [PDF]

Molecules
Ma X, Zhang Q, Yang Y, Zhan Y, Zhang X, Zhao Y, Li J, Wu D.   +7 more
europepmc   +1 more source