Results 231 to 240 of about 90,260 (324)

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

On the Formation of Double Neutron Stars in the Milky Way: Influence of Key Parameters [PDF]

Zhu-Ling Deng, Xiang‐Dong Li, Yong Shao, Kun Xu   +3 more
openalex   +3 more sources

Formation of a low-mass galaxy from star clusters in a 600-million-year-old Universe. [PDF]

Nature
Mowla L, Iyer K, Asada Y, Desprez G, Tan VYY, Martis N, Sarrouh G, Strait V, Abraham R, Bradač M, Brammer G, Muzzin A, Pacifici C, Ravindranath S, Sawicki M, Willott C, Estrada-Carpenter V, Jahan N, Noirot G, Matharu J, Rihtaršič G, Zabl J.   +21 more
europepmc   +1 more source

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

Advanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou, Yuqing Lv, Lin Li, Shukui Zhang, Jiaqi Liang, Chengchao Wu, Enyu Huang, Jianwei Jiao, Jingjing Zhang   +8 more
wiley   +1 more source

Nanovesicles and Human Skin Interaction: A Comparative Ex-Vivo Study. [PDF]

Nanomaterials (Basel)
Esposito E, Dzyhovski V, Santamaria F, Contado C, Brenna C, Neri LM, Secchiero P, Spinozzi F, Pepe A, Rawski M, Ortore MG, Mariani P, Galvan A, Calderan L, Malatesta M.   +14 more
europepmc   +1 more source

Reviving old controversies: is the early Galaxy flat or round? Investigations into the early phases of the Milky Way formation through stellar kinematics and chemical abundances [PDF]

, 2019
P. Di Matteo, M. Spite, M. Haywood, P. Bonifacio, A. Gómez, F. Spite, E. Caffau   +6 more
openalex  

Deacetylation of ACLY Mediates RNA M6A‐Modification of NOXA and Promotes Chemoresistance of Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the deacetylation of ACLY at K978 acts as a novel risk in colorectal cancer chemoresistance. The deacetylation of K978 induces ACLY relocation to the nucleus and promotes its binding to RBM15, a m6A methylation modification “writer”.
Jun Wen, Mengqin Shen, Haitao Zhao, Liu Liu, Qian Hua, Xiaoping Zhao, Jianjun Liu, Haizhong Feng, Gang Huang   +8 more
wiley   +1 more source

Multifunctional anionic nanoemulsion with linseed oil and lecithin: a preliminary approach for dry eye disease. [PDF]

Beilstein J Nanotechnol
Vasconcelos NF, Agrelli A, da Silva RCS, Mendes-Marques CL, Arruda IRS, de Oliveira PSS, de Oliveira ML, Machado G.   +7 more
europepmc   +1 more source

Anticodon Engineered Transfer RNA (tRNASUAG) Inhibits Hepatitis B Virus Replication by Promoting the Degradation of Core Protein

Advanced Science, EarlyView.
This study employed tRNASUAG, an anticodon‐engineered tRNA (ACE‐tRNA), to introduce a phosphorylatable serine into the C‐terminal domain of HBc by reading through its stop codon, thereby potentially promoting the ubiquitin‐proteasome degradation of HBc, and subsequently inhibiting HBV replication. Through a tRNASUAG‐gHBV1‐tRNASUAG‐gHBV2‐tRNASUAG tandem
Xingwen Yang, Huiying Sun, Ziheng Luo, Qinxin Zhang, Yarong Song, Jie Li, Xiaoyun Liu, Jie Wang   +7 more
wiley   +1 more source

Effects of trehalose supplementation on Pesisir bull sperm quality during storage. [PDF]

Open Vet J
Jaswandi, Masrizal, Ananda.
europepmc   +1 more source