Results 241 to 250 of about 92,409 (330)

OUR MILKY WAY AS A PURE-DISK GALAXY—A CHALLENGE FOR GALAXY FORMATION [PDF]

, 2010
Juntai Shen, R. Michael Rich, John Kormendy, Christian Howard, R. De Pietri, Andrea Kunder   +5 more
openalex   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Effect of Different Light Quality and Photoperiod on Mycelium and Fruiting Body Growth of Tricholoma giganteum. [PDF]

Life (Basel)
Luo Q, Zhan M, Yan S, Xie T, Huang X, Wang R, Lu H, Wang S, Lin J.   +8 more
europepmc   +1 more source

The formation of the Milky Way halo and its dwarf satellites, a NLTE-1D abundance analysis. I. Homogeneous set of atmospheric parameters

, 2017
L. Mashonkina, P. Jablonka, Yu. V. Pakhomov, T. Sitnova, P. North   +4 more
openalex   +2 more sources

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

Specific Spoilage Bacterium of Chilled Sturgeon Fillets and the Bacterial Reduction Effect of ClO₂. [PDF]

Food Sci Nutr
Yu S, Cen Q, Yu S, Hu W, Yin X, Shan M, Zeng X, Chen X.   +7 more
europepmc   +1 more source

Tables and Value-Added Catalogue from "J-PLUS: Reconstructing the Milky Way Disc's Star-Formation History with Twelve-Filter Photometry"

Jairo Andres, Alzate Trujillo, Hidalgo Pinilla, Adrian, del Pino Molina, Andrés, Centro de Estudios de Física del Cosmos de Aragón   +3 more
openalex   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Comparison of a new type of Dark Matter with the Milky Way and M31 grand rotation curves. [PDF]

Sci Rep
Law BM.
europepmc   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source