Results 91 to 100 of about 6,118 (224)
Da mímesis antiga à imitação dos antigos
Especiaria, 2015 Iniciando-se por um breve panorama dos usos filosóficos do termo mímesis na Antiguidade grega e passando em seguida pela explicitação das mais freqüentes interpretações da noção de mímesis que a modernidade europeia acabou por tornar consagradas a partir
Luisa Severo Buarque de Holanda
doaj
ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief
Advanced Science, EarlyView.ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng +19 more
wiley +1 more source
, 2018 International audienceAntonio Gramsci saw in the diva Lyda Borelli's acting the invention of a new gesturality whose expressiveness marked the emergence of a cinema based entirely on women's bodies: "In principio era il sesso", he wrote. With the arrival
Gailleurd, Céline
core
De la mimèsis á la contre-mimésis
プラトン以来, ミメーシスの問題は芸術の本質に関わるものとしてさまざまな議論を引き起こした。 19世紀まで, 対象を真似て描写することで成立すると見なされていた芸術は, オスカー・ワイルドの「芸術が本当に始まるのは, 模倣をやめたときである2)」という言葉に象徴されるように, 単なるコピーではなく, それ自体価値を持った領域として存続するようになる。 この変遷を, 19世紀から20世紀にかけてのフランスの絵画, 詩, さらに「純粋芸術」の概念の中に見ていく。|Depuis Platon, l ...
lNOUE, Naoko +2 more
core +1 more source
Advanced Science, EarlyView.Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong +20 more
wiley +1 more source
Della mimesis, in forma di primo editoriale
Mimesis Journal, 2012 Mimesis come conoscenza attraverso l’azione, attore come poeta, il teatro come veicolo di educazione in Aristotele come in Jerzy Grotowski. Aristotele sostiene che l’«imitazione di azioni e di vita» (mimesis) trova una sua compiutezza nella creazione ...
Antonio Attisani
doaj
Advanced Science, EarlyView.Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu +8 more
wiley +1 more source
An epidemiological model for mosquito host selection and temperature-dependent transmission of West Nile virus. [PDF]
Sci Rep, 2022 Fasano A +6 more
europepmc +1 more source
Advanced Science, EarlyView.This study uncovers a previously unrecognized copper‐COMMD1‐SOD1 regulatory axis, revealing that pathological copper overload paradoxically suppresses SOD1 activity by promoting COMMD1‐dependent disruption of SOD1 homodimerization. These findings redefine the regulatory role of copper in SOD1 biology and provide novel mechanistic insight into the ...
Yuqing Liu +7 more
wiley +1 more source
Advanced Science, EarlyView.A graphene‐based electrical biosensor enables rapid and highly sensitive detection of GHB at 100 fm in both standard solutions and artificial urine, providing reliable point‐of‐need screening for drug‐facilitated sexual assault. The platform demonstrates strong selectivity, fast response, and a wide dynamic range, supporting accurate detection in ...
Jai Eun An +8 more
wiley +1 more source