Results 191 to 200 of about 672,718 (300)

Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy

open access: yesAllergy, EarlyView.
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane   +12 more
wiley   +1 more source

Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin

open access: yesAllergy, EarlyView.
This study included 28 amoxicillin‐allergic patients and 11 healthy exposed controls. Mast cells were differentiated from CD34+ progenitors over 8 weeks using cytokine cocktails. The mast cell activation test involved sensitization with patient or control sera and stimulation with free amoxicillin or G4/G5‐AXO dendrimers with successfully activated ...
Jose A. Céspedes   +11 more
wiley   +1 more source

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): short‐term peri‐operative analgesic use

open access: yesAnaesthesia, EarlyView.
Summary Introduction An increasing proportion of complex surgical procedures are being performed in the UK as day‐cases, with variable and limited follow up. Discharge prescriptions must provide adequate analgesia, while considering the safety of the patient and public, following best practice guidance and good opioid stewardship.
Anna Ratcliffe   +2083 more
wiley   +1 more source

Factors associated with work-related musculoskeletal disorders using machine learning approaches: a systematic review. [PDF]

open access: yesAnn Occup Environ Med
Mohd Sallehhudin MI   +9 more
europepmc   +1 more source

Artificial Intelligence Models Using Magnetic Resonance Imaging to Predict Response to Chemoradiotherapy in Rectal Cancer: A Systematic Review

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background Pathological complete response (pCR) following neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer (LARC) is a key prognostic marker with implications for response‐adapted management. Although magnetic resonance imaging (MRI) is central to response assessment, differentiating residual tumour from treatment‐related
Winnie Lay   +4 more
wiley   +1 more source

Chromatinopathies: clinically overlapping disorders, revealing novel variants and their DNA methylation signatures. [PDF]

open access: yesClin Epigenetics
Koparir A   +20 more
europepmc   +1 more source

Identification and functional validation of a novel disease‐causing variant in the noncoding region of NYX

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of disorders, with ~30% of cases remaining genetically unsolved. Complete congenital stationary night blindness (cCSNB) is a subtype of IRD, usually associated with reduced visual acuity, nystagmus and high myopia.
Filip Spanic   +10 more
wiley   +1 more source

Unraveling the Genetic and Molecular Architecture of Autism Spectrum Disorder: Implications for Clinical Genetics and Genomic Diagnostics. [PDF]

open access: yesInt J Mol Sci
Treccarichi S   +15 more
europepmc   +1 more source

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