Results 221 to 230 of about 672,718 (300)
Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
Recovery After Transcervical Fibroid Ablation Versus Minimally Invasive Myomectomy for Symptomatic Uterine Fibroids: A Randomised Controlled Trial. [PDF]
Neis F +6 more
europepmc +1 more source
FVIIIa Mimetics: New Approaches and Next‐Generation Initiatives
ABSTRACT Emicizumab has revolutionized hemophilia A care, yet limitations regarding the “ceiling” of hemostatic efficacy (equivalent to mild hemophilia) and global access persist. This review critically examines two distinct paradigms shaping the future of care: Innovation and Access. Regarding innovation, we synthesize the latest clinical data on next‐
Tadashi Matsushita +2 more
wiley +1 more source
Efficient cellular transformation via protein delivery through the protrusion-derived extracellular vesicles. [PDF]
Fujioka T +11 more
europepmc +1 more source
Aging of bone density (BV/TV) is regional: Forelimb [left] elements gain bone sporadically (orange) but hind limb elements [right] lose bone globally (blue). Abstract Globally, human population structure is quickly trending older, increasing the prevalence and systemic burden of age‐related skeletal disorders such as osteoporosis.
Cassandra M. Turcotte +16 more
wiley +1 more source
A national biobank framework for rare diseases: Standardized infrastructure and cross-institutional collaboration accelerating translational innovation in China. [PDF]
Liu W +9 more
europepmc +1 more source
SUBDUE‐3: SUB‐urothelial DUrvalumab‐89zirconium injEction; a phase 0 biodistribution study protocol
BJU International, EarlyView.
Kevin G. Keane +9 more
wiley +1 more source
ABSTRACT The concept of humility has a long history of paradoxicality. From denoting a lowly social status—to becoming one of the highest Christian virtues—to falling under the critique of the liberators of the Enlightenment—to experiencing an upsurge of philosophical and psychological interest in recent years, the value of acknowledging one's least ...
Benjamin Birkenstock
wiley +1 more source

