Results 101 to 110 of about 944,278 (274)
Endogenous security architecture of Ethernet switch based on mimic defense
Tongxin xuebao, 2020 Aiming at the unknown vulnerabilities and unknown backdoor security threats faced by Ethernet switches,a switch endogenous security architecture based on mimicry defense theory was proposed.The theoretical basis,construction mode and security mechanism ...
Ke SONE +4 more
doaj
Defense-enhanced dynamic heterogeneous redundancy architecture based on executor partition
Tongxin xuebao, 2021 Aiming at the security problem when servants are faced with common vulnerabilities, an improved DHR architecture called IDHR was proposed.On the basis of DHR, an executor-partition module that divided the executor-set to several executor pools by the ...
Ting WU +4 more
doaj
Advanced Science, EarlyView.Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen +20 more
wiley +1 more source
Design and implementation of adaptive mimic voting device oriented to persistent connection
Tongxin xuebao, 2022 Objectives: Mimic voter is a crucial component under the dynamic heterogeneous redundancy architecture of mimic defense technology,but the existing mimic voting method needs to collect and process the complete output data of heterogeneous redundant ...
Dacheng ZHOU +5 more
doaj
Advanced Science, EarlyView.This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan +17 more
wiley +1 more source
Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Advanced Science, EarlyView.Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source
J.B. McNamara from International Labor Defense, January 11, 1936-April 12, 1940
, 2021 Letters to J.B.
International Labor Defense
core
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Advanced Science, EarlyView.In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang +11 more
wiley +1 more source