Results 181 to 190 of about 159,089 (292)

Neoplastic Immune Mimicry Potentiates Breast Tumor Progression. [PDF]

Cancer Res
Berens EB, Khou S, Huang ET, Hoffman A, Johnson B, Kirchberger N, Sivagnanam S, Calistri NL, Derrick DS, Liby TA, McLean IC, Alanizi AA, Ozmen F, Ozmen TY, Mills GB, Hwang ES, Schedin P, Gonzalez H, Werb Z, Heiser LM, Coussens LM.   +20 more
europepmc   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

Impairment of the Uroporphyrinogen Decarboxylase 2 Gene Induces Lesion Mimicry and Downregulates Tetrapyrrole Biosynthesis Pathway Genes in Rice. [PDF]

Rice (N Y)
Qu M, Lin Y, Lin R, Song D, Zhang H, Yang F, Chen Z, Tang W, Han Y, Li W, Wang Z, Lu G, Chen S.   +12 more
europepmc   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

Advanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong, Jingyi Lu, Haopeng Li, Jun Zhong, Xiaobei Luo, Yiyi Hu, Xianfei Wang, Pengfei Wang, Yanning Zhang, Zhenjiang Wang, Qiuhua Lai, Zhenyu Chen, Wenting Mi, Wang Tin San‐to, Weize Li, Shuping Tan, Qihong Cheng, Ruijia Li, Yida Nie, Side Liu, Bing Huang, Zelong Han   +21 more
wiley   +1 more source

mimicDetector: a pipeline for protein motif mimicry detection in host-pathogen interactions. [PDF]

Bioinformatics
Rich KD, Wasmuth JD.
europepmc   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Facial mimicry predicts preference. [PDF]

Commun Psychol
Amihai L, Sharvit E, Man H, Hanein Y, Yeshurun Y.   +4 more
europepmc   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

The genetic basis of mimicry in the snowy bumble bee (Bombus niveatus) in Anatolia with insights from a color polymorphic gynandromorph. [PDF]

PLoS Genet
Dabak T, Özenirler Ç, Kamalak E, Smith C, Aytekin S, Aytekin AM, Hines HM.   +6 more
europepmc   +1 more source

Linking Plant Metabolomics with Fungal Functional Dynamics Reveals a Noncanonical S‐R‐C Adaptive Trajectory

Advanced Science, EarlyView.
Using field‐based holo‐omics, we demonstrate that developmental shifts in sorghum leaf metabolomes drive a noncanonical fungal succession from stress tolerators (S) through ruderals (R) to competitors (C). Antifungal metabolites in young leaves select for S strategists with expanded genomes, transient maltose pulses during flowering favor fast‐growing ...
Peilin Chen, John W. Taylor, Cheng Gao
wiley   +1 more source