Results 131 to 140 of about 1,877 (147)

Mimivirus

2009
Acanthamoeba polyphaga Mimivirus, the first representative and prototype member of the Mimiviridae, is the latest addition to the menagerie of lesser-known big DNA viruses. Due to the size of its particle--a fiber-covered icosahedral protein capsid with a diameter of 0.7 microm--Mimivirus was initially mistaken for an intracellular parasitic bacteria ...
J M, Claverie, C, Abergel, H, Ogata
openaire   +2 more sources

Redefining viruses: lessons from Mimivirus

Nature Reviews Microbiology, 2008
Viruses are the most abundant living entities and probably had a major role in the evolution of life, but are still defined using negative criteria. Here, we propose to divide biological entities into two groups of organisms: ribosome-encoding organisms, which include eukaryotic, archaeal and bacterial organisms, and capsid-encoding organisms, which ...
Raoult, Didier, Forterre, Patrick
openaire   +2 more sources

Genomic and evolutionary aspects of Mimivirus

Virus Research, 2006
We recently described a giant double stranded DNA virus called Mimivirus, isolated from amoebae, which might represent a new pneumonia-associated human pathogen. Its unique morphological and genomic characteristics allowed us to propose Mimivirus as a member of a new distinct Nucleocytoplasmic Large DNA viruses family, the Mimiviridae.
M, Suzan-Monti, B, La Scola, D, Raoult
openaire   +2 more sources

The 1.2-Megabase Genome Sequence of Mimivirus

Science, 2004
We recently reported the discovery and preliminary characterization of Mimivirus, the largest known virus, with a 400-nanometer particle size comparable to mycoplasma. Mimivirus is a double-stranded DNA virus growing in amoebae. We now present its 1,181,404–base pair genome sequence, consisting of 1262 putative open reading frames, 10% of which exhibit
Didier, Raoult, Stéphane, Audic, Catherine, Robert, Chantal, Abergel, Patricia, Renesto, Hiroyuki, Ogata, Bernard, La Scola, Marie, Suzan, Jean-Michel, Claverie   +8 more
openaire   +2 more sources

Cryo-electron Microscopy of the Giant Mimivirus

Journal of Molecular Biology, 2005
Mimivirus is the largest known virus. Using cryo-electron microscopy, the virus was shown to be icosahedral, covered by long fibers, and appears to have at least two lipid membranes within its protein capsid. A unique vertex, presumably for attachment and infection of the host, can be seen for particles that have a suitable orientation on the ...
Chuan, Xiao, Paul R, Chipman, Anthony J, Battisti, Valorie D, Bowman, Patricia, Renesto, Didier, Raoult, Michael G, Rossmann   +6 more
openaire   +2 more sources

Oysters as hot spots for mimivirus isolation

Archives of Virology, 2014
Viruses are ubiquitous organisms, but their role in the ecosystem and their prevalence are still poorly understood. Mimiviruses are extremely complex and large DNA viruses. Although metagenomic studies have suggested that members of the family Mimiviridae are abundant in oceans, there is a lack of information about the association of mimiviruses with ...
Kétyllen R, Andrade, Paulo P V M, Boratto, Felipe P, Rodrigues, Lorena C F, Silva, Fábio P, Dornas, Mariana R, Pilotto, Bernard, La Scola, Gabriel M F, Almeida, Erna G, Kroon, Jônatas S, Abrahão   +9 more
openaire   +2 more sources

Mimivirus: the emerging paradox of quasi-autonomous viruses

Trends in Genetics, 2010
What is a virus? Are viruses alive? Should they be classified among microorganisms? One would expect these simple questions to have been settled a century after the discovery of the first viral disease. For years, modern virology successfully unravelled the huge diversity of viruses in terms of genetic material, replication mechanism, pathogenicity ...
Jean-Michel, Claverie, Chantal, Abergel
openaire   +2 more sources

Mimivirus et l’histoire du vivant

Antibiotiques, 2007
Resume Objectifs Il s’agit d’une revue destinee a rappeler les definitions et les caracteristiques microscopiques, physiologiques et genomiques du vaste groupe forme par les virus, les Eukaryotes , Prokaryotes et Archae , auxquels les auteurs ont ajoute Mimivirus , dont la mise en evidence souleve de nouvelles questions phylogeniques et ...
openaire   +1 more source

Mimivirus-Encoded Nucleotide Translocator VMC1 Targets the Mitochondrial Inner Membrane

Journal of Molecular Biology, 2018
Mimivirus (Acanthamoeba polyphaga mimivirus) was the first giant DNA virus identified in an amoeba species. Its genome contains at least 979 genes. One of these, L276, encodes a nucleotide translocator with similarities to mitochondrial metabolite carriers, provisionally named viral mitochondrial carrier 1 (VMC1).
Zara, Vincenzo, Ferramosca, Alessandra, Günnewig, Kathrin, Kreimendahl, Sebastian, Schwichtenberg, Jan, Sträter, Dina, Çakar, Mahmut, Emmrich, Kerstin, Guidato, Patrick, Palmieri, Ferdinando, Rassow, Joachim.   +10 more
openaire   +2 more sources

Pneumonia in mice inoculated experimentally with Acanthamoeba polyphaga mimivirus

Microbial Pathogenesis, 2007
In an attempt to elucidate whether Acanthamoeba polyphaga mimivirus (APM) was pathogenic (i.e., induces histological evidence of inflammation or tissue destruction or both) in mammalian host, we inoculated adult BALB/c (n=6) and C57BL/6 (n=6) mice with APM via intracardiac route.
Mohammad, Khan, Bernard, La Scola, Hubert, Lepidi, Didier, Raoult   +3 more
openaire   +2 more sources