Results 31 to 40 of about 4,249 (213)

Membrane assembly during the infection cycle of the giant Mimivirus. [PDF]

PLoS Pathogens, 2013
Although extensively studied, the structure, cellular origin and assembly mechanism of internal membranes during viral infection remain unclear. By combining diverse imaging techniques, including the novel Scanning-Transmission Electron Microscopy ...
Yael Mutsafi, Eyal Shimoni, Amir Shimon, Abraham Minsky   +3 more
doaj   +4 more sources

Presence of CRISPR CAS-Like Sequences as a Proposed Mechanism for Horizontal Genetic Exchanges between Trichomonas vaginalis and Its Associated Virus: A Comparative Genomic Analysis with the First Report of a Putative CRISPR CAS Structures in Eukaryotic Cells. [PDF]

Biomed Res Int, 2023
Introduction. Trichomonas vaginalis genome is among the largest genome size and coding capacities. Combinations of gene duplications, transposon, repeated sequences, and lateral gene transfers (LGTs) have contributed to the unexpected large genomic size and diversity. This study is aimed at investigating genomic exchange and seeking for presence of the
Kenarkoohi A, Abdoli A, Rostamzad A, Rashnavadi M, Naserifar R, Abdi J, Shams M, Bozorgomid A, Saeb S, Al-Fahad D, Khezri K, Falahi S.   +11 more
europepmc   +2 more sources

Hybrid Sequencing Resolved Inverted Terminal Repeats in the Genome of Megavirus Baoshan

Frontiers in Microbiology, 2022
Mimivirus is a group of amoeba-infecting DNA viruses with linear double-strand genome. It is found to be ubiquitous in nature worldwide. Here, we reported the complete genome of a new member of Mimivirus lineage C isolated from a fresh water pond in ...
Yucheng Xia, Huanyu Cheng, Jiang Zhong
doaj   +1 more source

Water, Water Everywhere, but Every Drop Unique: Challenges in the Science to Understand the Role of Contaminants of Emerging Concern in the Management of Drinking Water Supplies

GeoHealth, Volume 7, Issue 12, December 2023., 2023
Abstract The protection and management of water resources continues to be challenged by multiple and ongoing factors such as shifts in demographic, social, economic, and public health requirements. Physical limitations placed on access to potable supplies include natural and human‐caused factors such as aquifer depletion, aging infrastructure ...
Susan T. Glassmeyer, Emily E. Burns, Michael J. Focazio, Edward T. Furlong, Matthew O. Gribble, Michael A. Jahne, Scott P. Keely, Alison R. Kennicutt, Dana W. Kolpin, Elizabeth K. Medlock Kakaley, Stacy L. Pfaller   +10 more
wiley   +1 more source

From viral democratic genomes to viral wild bunch of quasispecies

Journal of Medical Virology, Volume 95, Issue 11, November 2023., 2023
Abstract The tremendous majority of RNA genomes from pathogenic viruses analyzed and deposited in databases are consensus or “democratic” genomes. They represent the genomes most frequently found in the clinical samples of patients but do not account for the huge genetic diversity of coexisting genomes, which is better described as quasispecies.
Philippe Colson, Wahiba Bader, Jacques Fantini, Pierre Dudouet, Anthony Levasseur, Pierre Pontarotti, Christian Devaux, Didier Raoult   +7 more
wiley   +1 more source

A rapid genome‐wide analysis of isolated giant viruses using MinION sequencing

Environmental Microbiology, Volume 25, Issue 11, Page 2621-2635, November 2023., 2023
We evaluated performance of MinION sequencing for giant virus genomics. Re‐sequencing of a prototype marseillevirus by MinION alone provided high‐quality genomes. As a proof of concept, we sequenced genomes of newly isolated giant viruses. Collectively, we concluded that MinION sequencing is an effective approach to rapidly perform a genome‐wide ...
Hiroyuki Hikida, Yusuke Okazaki, Ruixuan Zhang, Thi Tuyen Nguyen, Hiroyuki Ogata   +4 more
wiley   +1 more source

The return of the “Mistigri” (virus adaptative gain by gene loss) through the SARS‐CoV‐2 XBB.1.5 chimera that predominated in 2023

Journal of Medical Virology, Volume 95, Issue 10, October 2023., 2023
Abstract Severe acute respiratory syndrome coronavirus 2 XBB.1.5 is the first recombinant lineage to predominate at the country and global scales. Very interestingly, like the Marseille‐4B subvariant (or B.1.160) and the pandemic variant B.1.1.7 (or Alpha) previously, it has its ORF8 gene inactivated by a stop codon.
Philippe Colson, Jérémy Delerce, Jacques Fantini, Pierre Pontarotti, Bernard La Scola, Didier Raoult   +5 more
wiley   +1 more source

Three-dimensional reconstruction of the giant mimivirus particle with an X-ray free-electron laser [PDF]

, 2015
10.1103/PhysRevLett.114.098102Physical Review ...
Abergel, Chantal, Andersson, Inger, Barty, Anton, Bostedt, Christoph, Bozek, John, Chapman, Henry, Claverie, Jean-Michel, Deponte, Daniel, Ekeberg, Tomas, Epp, Sascha, Ferguson, Ken, Hajdu, Janos, Hantke, Max, Hartmann, Robert, Iwan, Bianca, Jönsson, Olof, Kauffmann, Martin, Kimmel, Nils, Krzywinski, Jacek, Liang, Mengning, Loh, N Duane, Loh, N. Duane, Maia, Filipe, Maia, Filipe R. n. c., Martin, Andrew, Nettelblad, Carl, Rolles, Daniel, Rudenko, Artem, Seibert, M Marvin, Seibert, M. Marvin, Seltzer, Virginie, van Der Schot, Gijs   +31 more
core   +10 more sources

Scanning transmission electron tomography to study virus assembly: Review for the retirement of Paul Walther. [PDF]

J Microsc
Abstract In this short and popular review, we summarise some of our findings analysing the replication cycles of large DNA viruses using scanning transmission electron tomography (STEM tomography) that we applied in the laboratory of Paul Walther. It is also a tribute to a very kind and expert scientist, who recently retired.
Wieczorek S, Krijnse Locker J.
europepmc   +2 more sources

Pleistocene glacial and interglacial ecosystems inferred from ancient DNA analyses of permafrost sediments from Batagay megaslump, East Siberia

Environmental DNA, Volume 4, Issue 6, Page 1265-1283, November 2022., 2022
As the past is the key to the future, to understand community transformations and ecological interactions, we reconstructed ecosystem‐wide biotic composition (from viruses to megaherbivores) between glacials and interglacials from the Middle and Late Pleistocene at the Batagay megaslump, east Siberia.
Jérémy Courtin, Amedea Perfumo, Andrei A. Andreev, Thomas Opel, Kathleen R. Stoof‐Leichsenring, Mary E. Edwards, Julian B. Murton, Ulrike Herzschuh   +7 more
wiley   +1 more source