Results 31 to 40 of about 3,644 (165)

The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield

open access: yeseLife, 2022
Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses. Little is known about the organization of the 1.2 Mb genome inside the membrane-limited nucleoid filling the ~0.5 µm icosahedral capsids. Cryo-electron microscopy, cryo-electron
Alejandro Villalta   +13 more
doaj   +1 more source

Exposure to Mimivirus collagen promotes arthritis [PDF]

open access: yes, 2014
Collagens, the most abundant proteins in animals, also occur in some recently described nucleocytoplasmic large DNA viruses such as Mimiviridae, which replicate in amoebae.
Gay, Steffen   +5 more
core   +1 more source

Mimivirus in Pneumonia Patients

open access: yesEmerging Infectious Diseases, 2005
Mimivirus, the largest virus known to date, is an amebal pathogen like Legionella spp. When mimivirus was used as an antigen in a migration inhibition factor assay, seroconversion was found in patients with both community- and hospital-acquired pneumonia.
Bernard La Scola   +3 more
doaj   +1 more source

Microscopic Characterization of the Brazilian Giant Samba Virus

open access: yesViruses, 2017
Prior to the discovery of the mimivirus in 2003, viruses were thought to be physically small and genetically simple. Mimivirus, with its ~750-nm particle size and its ~1.2-Mbp genome, shattered these notions and changed what it meant to be a virus. Since
Jason R. Schrad   +4 more
doaj   +1 more source

Machine learning for ultrafast X-ray diffraction patterns on large-scale GPU clusters [PDF]

open access: yes, 2014
The classical method of determining the atomic structure of complex molecules by analyzing diffraction patterns is currently undergoing drastic developments.
Ekeberg, Tomas   +2 more
core   +1 more source

Pulmonary Infection Related to Mimivirus in Patient with Primary Ciliary Dyskinesia

open access: yesEmerging Infectious Diseases, 2020
Primary ciliary dyskinesia is a rare autosomal recessive disorder that causes oto-sino-pulmonary disease. We report a case of pulmonary infection related to mimivirus in a 10-year-old boy with primary ciliary dyskinesia that was identified using ...
Fatemeh Sakhaee   +4 more
doaj   +1 more source

Mimivirus relatives in the Sargasso sea

open access: yesVirology Journal, 2005
The discovery and genome analysis of Acanthamoeba polyphaga Mimivirus, the largest known DNA virus, challenged much of the accepted dogma regarding viruses. Its particle size (>400 nm), genome length (1.2 million bp) and huge gene repertoire (911 protein
Claverie Jean-Michel, Ghedin Elodie
doaj   +1 more source

A new example of viral intein in Mimivirus

open access: yesVirology Journal, 2005
Background Inteins are "protein introns" that remove themselves from their host proteins through an autocatalytic protein-splicing. After their discovery, inteins have been quickly identified in all domains of life, but only once to date in the genome of
Claverie Jean-Michel   +2 more
doaj   +1 more source

Comparative genomic and biochemical analyses identify a collagen galactosylhydroxylysyl glucosyltransferase from Acanthamoeba polyphaga mimivirus

open access: yesScientific Reports, 2022
Humans and Acanthamoeba polyphaga mimivirus share numerous homologous genes, including collagens and collagen-modifying enzymes. To explore this homology, we performed a genome-wide comparison between human and mimivirus using DELTA-BLAST (Domain ...
Wenhui Wu   +10 more
doaj   +1 more source

Role of the R349 Gene and Its Repeats in the MIMIVIRE Defense System

open access: yesFrontiers in Microbiology, 2019
MIMIVIRE is a defense system described in lineage A Mimivirus (Mimiviridae family) that mediates resistance against Zamilon virophage. It is composed of putative helicase and nuclease associated with a gene of unknown function called R349, which contains
Said Mougari   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy