Results 31 to 40 of about 3,644 (165)
Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses. Little is known about the organization of the 1.2 Mb genome inside the membrane-limited nucleoid filling the ~0.5 µm icosahedral capsids. Cryo-electron microscopy, cryo-electron
Alejandro Villalta +13 more
doaj +1 more source
Exposure to Mimivirus collagen promotes arthritis [PDF]
Collagens, the most abundant proteins in animals, also occur in some recently described nucleocytoplasmic large DNA viruses such as Mimiviridae, which replicate in amoebae.
Gay, Steffen +5 more
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Mimivirus in Pneumonia Patients
Mimivirus, the largest virus known to date, is an amebal pathogen like Legionella spp. When mimivirus was used as an antigen in a migration inhibition factor assay, seroconversion was found in patients with both community- and hospital-acquired pneumonia.
Bernard La Scola +3 more
doaj +1 more source
Microscopic Characterization of the Brazilian Giant Samba Virus
Prior to the discovery of the mimivirus in 2003, viruses were thought to be physically small and genetically simple. Mimivirus, with its ~750-nm particle size and its ~1.2-Mbp genome, shattered these notions and changed what it meant to be a virus. Since
Jason R. Schrad +4 more
doaj +1 more source
Machine learning for ultrafast X-ray diffraction patterns on large-scale GPU clusters [PDF]
The classical method of determining the atomic structure of complex molecules by analyzing diffraction patterns is currently undergoing drastic developments.
Ekeberg, Tomas +2 more
core +1 more source
Pulmonary Infection Related to Mimivirus in Patient with Primary Ciliary Dyskinesia
Primary ciliary dyskinesia is a rare autosomal recessive disorder that causes oto-sino-pulmonary disease. We report a case of pulmonary infection related to mimivirus in a 10-year-old boy with primary ciliary dyskinesia that was identified using ...
Fatemeh Sakhaee +4 more
doaj +1 more source
Mimivirus relatives in the Sargasso sea
The discovery and genome analysis of Acanthamoeba polyphaga Mimivirus, the largest known DNA virus, challenged much of the accepted dogma regarding viruses. Its particle size (>400 nm), genome length (1.2 million bp) and huge gene repertoire (911 protein
Claverie Jean-Michel, Ghedin Elodie
doaj +1 more source
A new example of viral intein in Mimivirus
Background Inteins are "protein introns" that remove themselves from their host proteins through an autocatalytic protein-splicing. After their discovery, inteins have been quickly identified in all domains of life, but only once to date in the genome of
Claverie Jean-Michel +2 more
doaj +1 more source
Humans and Acanthamoeba polyphaga mimivirus share numerous homologous genes, including collagens and collagen-modifying enzymes. To explore this homology, we performed a genome-wide comparison between human and mimivirus using DELTA-BLAST (Domain ...
Wenhui Wu +10 more
doaj +1 more source
Role of the R349 Gene and Its Repeats in the MIMIVIRE Defense System
MIMIVIRE is a defense system described in lineage A Mimivirus (Mimiviridae family) that mediates resistance against Zamilon virophage. It is composed of putative helicase and nuclease associated with a gene of unknown function called R349, which contains
Said Mougari +5 more
doaj +1 more source

