Results 181 to 190 of about 58,991,248 (234)

Underexplored Ligand-Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach. [PDF]

ChemMedChem
Leite PTTF, Ocarino LHS, Veríssimo GC, Fernandes PO, Pereira DF, Oliveira FKME, Marbán-González A, Medina-Franco JL, Serafim MSM, Kronenberger T, Maltarollo VG.   +10 more
europepmc   +1 more source

Synthesis of Nitrogen‐Containing Heterocyclic Scaffolds and Applications in Scaffold Hopping: Development of an Aripiprazole Analog

ChemMedChem, Volume 21, Issue 20, 28 October 2026.
A series of 12 novel fused [6,6] saturated and unsaturated nitrogen bicycles is synthesized in three to five steps and expands the CRAFT library's fragment space. A 2,6‐naphthyridin‐3‐ol core replaces the dihydroquinolinone scaffold of aripiprazole, a scaffold‐hopping strategy.
Temitayo Omowumi Alegbejo Price, Pieterjan Winant, Paulo Eliandro da Silva Júnior, Shaiani Maria Gil de Melo, Pedro Henrique Gobira, Julia Possamai Gimenes, Pedro Tenório Teixeira Fernandes Leite, Vinícius Gonçalves Maltarollo, Gustavo Henrique Goulart Trossini, A. Ganesan, Sâmia Regiane Lourenço Joca, Wim Dehaen, Flavio da Silva Emery   +12 more
wiley   +1 more source

Co-BDC MOF/Graphene Nanohybrid as an Efficient Electrode Material for High-Performance Supercapacitors. [PDF]

ACS Omega
Braga AL, Lima TAS, Fortunato VDS, Justino DD, Gomes PGR, Silva RCF, Vieira LFMA, Ribeiro H, Teixeira APC, Ortega PFR, Lavall RL, Mambrini RV, Trigueiro JPC.   +12 more
europepmc   +1 more source

Valorization of Post‐Consumer Waste From Metallized Flexible Packaging and Industrial EPM Waste: Development of Sustainable Composites

Journal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
Post‐consumer metallized flexible packaging waste and industrial EPM waste are transformed into sustainable composites through mechanical recycling. The incorporation of 30 wt% EPM provides the most favorable balance between stiffness, ductility, and impact resistance, achieving 53.36 kJ/m2.
Tiago O. Oliveira, Samara L. Santos, Ruth M. C. Santana   +2 more
wiley   +1 more source

Behind Tolerance and the Cost of Coexistence: The Cd-Mn Interaction in Sunflower Triggers Translocation Reconfiguration, Impacting Productivity and Food Security. [PDF]

J Agric Food Chem
Pereira AAS, Bernardes MM, Silva VN, Ferreira RA, Nery FC, Pereira EG, Bicalho EM.   +6 more
europepmc   +1 more source

Factores que influyen en la acumulación de biomasa de herbáceas durante la sucesión en minas de carbón

Ecosistemas, 2010
Y. Pallavacini
doaj  

Electrosynthesis of Functionalized Chromenes via Selenylation-Induced Alkynes Cyclization. [PDF]

J Org Chem
Martins GM, de Lucca F, Ribeiro JPRS, de Castro PP, de Lima M, Mendes SR, Berlinck RGS, de Oliveira KT.   +7 more
europepmc   +1 more source

Synthesis, Antiparasitic Activity, and ADME Profile of Morpholinephenylbenzamides: A Pharmacological Study Against Chagas Disease and Visceral Leishmaniasis

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Hit‐to‐lead optimization of morpholinephenylbenzamides reveals key structure–activity relationships against Trypanosoma cruzi and Leishmania infantum. Potency, selectivity, and ADME properties are differentially improved across the series, identifying compounds 20, 24, and 16 as complementary templates for the future design of dual antiparasitic leads.
Danilo Nascimento Farago, Daniela de Melo Resende, Mariza Gabriela Faleiro de Moura Lodi Cruz, Rafaela Marçal Sousa, Rafael Consolin Chelucci, Simone Michelan‐Duarte, Felipe da Silva Mendonça de Melo, Douglas Davison da Silva Oliveira, Paula Derksen Macruz, Alexandra Maria dos Santos Carvalho, Eduardo Jorge Pilau, Izabela Marques Dourado Bastos, Adriano D. Andricopulo, Leonardo L. G. Ferreira, Silvane Maria Fonseca Murta, Celso de Oliveira Rezende Júnior   +15 more
wiley   +1 more source

Methamphetamine Enantiomers: From Chemical Synthesis to Biological Fate. [PDF]

Chirality
do Espírito Santo LP, de Carvalho RL, Sad JA, Dos Santos PHC, Domingues RS, de Azevedo Cardoso G, Enes KB, Goulart GAC, de Castro Lourenço das Neves M, de Fátima Â.   +9 more
europepmc   +1 more source

Synthesis of Naphthoquinones by Pd‐Catalyzed Heck–Matsuda Arylation of Lapachol

European Journal of Organic Chemistry, Volume 29, Issue 38, 13 October 2026.
Direct Heck–Matsuda arylation of lapachol enables the efficient synthesis of diverse naphthoquinones under homogeneous and heterogeneous palladium catalysis. The methodology features broad substrate scope, gram‐scale applicability, and provides a practical platform for quinone diversification.
Breno U. de Abreu, Renata G. Almeida, Ana L. C. Silveira, Leonardo A. Matos, Willian X. C. Oliveira, Maria H. Araujo, Victor F. S. Ramos, Rubem F. S. Menna‐Barreto, Chandrakant B. Nichinde, Felipe Fantuzzi, Edmond Gravel, Eric Doris, Eufrânio N. da Silva Júnior, Guilherme A. M. Jardim   +13 more
wiley   +1 more source