Results 101 to 110 of about 54,916 (245)

Noninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study

open access: yesHepatology Communications, EarlyView., 2022
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk   +6 more
wiley   +1 more source

Efficacy of Mind-body Exercise to Reduce Sleep Disturbance and Depression Among Older Adults: A Systematic Review and Meta-analysis

open access: yesAsian Nursing Research
Summary: Purpose: Mind-body exercise is a promising non-pharmacological approach for managing sleep disturbance and depression that are prevalent among older adults, but its efficacy remains inconclusive across the studies.
Makhfudli Makhfudli   +4 more
doaj   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

open access: yesBiotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson   +7 more
wiley   +1 more source

“It's Like Learning a Whole New Language”: Bilingual Counselors‐in‐Training in a Spanish Internship Course

open access: yesCounselor Education and Supervision, EarlyView.
ABSTRACT This phenomenological study explored the lived experiences of bilingual Spanish‐speaking counselors‐in‐training (BS‐CITs) enrolled in a Spanish internship course within a Bilingual Counseling Certificate program. Participants included nine master's‐level counseling students who completed individual, semi‐structured interviews.
Claudia G. Interiano‐Shiverdecker   +2 more
wiley   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović   +11 more
wiley   +1 more source

Insights and Future Directions on the Combined Effects of Mind-Body Therapies with Transcranial Direct Current Stimulation: An Evidence-based Review. [PDF]

open access: yesJ Int Soc Phys Rehabil Med, 2022
Rebello-Sanchez I   +8 more
europepmc   +1 more source

Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug Exposure

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
This study investigated genetic determinants of the pharmacokinetics of the CYP2C8 index drugs repaglinide and gemfibrozil, and their interaction in healthy participants. Sequencing data from a study with montelukast revealed a novel functional CYP2C8 allele (rs2071426, CYP2C8*19), predicted to create an intronic splice donor site.
Anssi J. H. Mykkänen   +14 more
wiley   +1 more source

Health and quality of life promotion for old people using bodily practices

open access: yesO Mundo da Saúde, 2014
The increasing of the elderly population is related to better material conditions for survival and progress of health practices. Bodily practices are recognized as an important strategy for health promotion and disease prevention for this population ...
Rosé Colom Toldrá   +3 more
doaj  

Optimal doses of mind-body exercise on neuroinflammation in individuals with neuropsychiatric disorders: A systematic review and dose-response meta-analysis

open access: yesBrain, Behavior, & Immunity - Health
Background: Mind-body exercises (MBEs), including Tai Chi (TC), Qigong (QG), Yoga (YG), and Mindfulness-Based Stress Reduction (MBSR), show promise in neuropsychiatric rehabilitation by modulating neuroinflammation. This study systematically examines the
Qingying Zheng   +4 more
doaj   +1 more source

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