Results 111 to 120 of about 450,539 (268)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Design of Test Tooling of Mine-used Equipment On/Off Transducer
Gong-kuang zidonghua, 2012 Traditional testing method of mine-used equipment on/off transducer needs three-phase AC power supply and electric fires or bulbs with large power to get current for transducer acting, which cannot get continuously adjustable current with complex wiring ...
CHU Wei-zhong +3 more
doaj
Performance criteria guideline for three explosion protection methods of electrical equipment rated up to 15,000 volts AC [PDF]
The Bureau of Mines, U.S. Department of the Interior, is reviewing explosion protection methods for use in gassy coal mines. This performance criteria guideline is an evaluation of three explosion protection methods of machines electrically powered with ...
Dunn, J. H., Linley, L. J., Luper, A. B.
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Design of an Environment Monitoring and Control Device of Mined-used Lifesaving Cabi
Gong-kuang zidonghua, 2011 In view of problems of bad coordination existed in current environment monitoring and control device of mine-used lifesaving cabin in China, the paper proposed a new type of design scheme of environment monitoring and control device of mine-used ...
ZHANG Li-bi
doaj
THE INVESTMENT PROJECT PIPELINE COST ESCALATION, LEAD-TIME, SUCCESS, FAILURE AND SPEED1 [PDF]
As they involve expectations about the future and long lead times for planning and construction, the evolution of investment projects is usually complex and volatile.
Jiawei Si, Kenneth W Clements
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Auctioning Rough Diamonds: A Competitive Sales Process for BHP Billiton’s Ekati Diamonds [PDF]
We describe a new approach for selling rough diamonds through competitive auctions. The classical approach of De Beers—giving each customer a bag of stones and a take-it-or-leave-it price—worked well in near monopoly circumstances, but is ill-suited for ...
Peter Cramton +2 more
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Recovery of Water and Salt from Hyper-Saline Mine Water using Freeze Crystallization [PDF]
, 2019 The Freezerbacks researched, designed, and economically evaluated a full-scale freeze crystallization process as well as two alternative full-scale processes: 5 stage multiple effect evaporation and reverse osmosis.
Casey, Gabrielle
core +2 more sources