Results 101 to 110 of about 25,335,002 (250)

Research on formation process of arc grounding over-voltage in mine power supply system

open access: yes, 2018
For comprehensive research on formation process of arc grounding over-voltage in mine power supply system, a mine power supply system model and an intermittent arc grounding model were built by use of real time digital simulator, and over-voltages in ...
LIU Jucai   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Report on the Little Mattie mine

open access: yes, 2022
Mine report no. 782.Typescript (carbon copy).The property was located about two and a half miles southwest of Idaho Springs in the Jackson mining district, Clear Creek County, Colorado. Names of the seventeen mining claims were not given. Includes a copy
Knight, D. Atwood
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Potential Carbon Sequestration and Revenue from Timber and Carbon Credits for Landowners of West Virginia Abandoned Mine Lands. [PDF]

open access: yes
An optimal forest rotation model estimates potential value from timber and carbon for owners of WV abandoned mine lands (AMLs). An OLS regression provides merchantable volume and carbon density for six forest types which could sequester 0.41 Tg of carbon
Bouquot, Chris, Sperow, Mark
core  

Design of Test Tooling of Mine-used Equipment On/Off Transducer

open access: yesGong-kuang zidonghua, 2012
Traditional testing method of mine-used equipment on/off transducer needs three-phase AC power supply and electric fires or bulbs with large power to get current for transducer acting, which cannot get continuously adjustable current with complex wiring ...
CHU Wei-zhong   +3 more
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Design of an Environment Monitoring and Control Device of Mined-used Lifesaving Cabi

open access: yesGong-kuang zidonghua, 2011
In view of problems of bad coordination existed in current environment monitoring and control device of mine-used lifesaving cabin in China, the paper proposed a new type of design scheme of environment monitoring and control device of mine-used ...
ZHANG Li-bi
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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