Results 111 to 120 of about 25,335,002 (250)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
LEPA-MX1-DC-POWER-SUPPLY-12V-CONVERSION
, 2018 Conversion Process for Lepa MX1 Computer Power ...
Cory Andrew Hofstad (5368814)
core +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Fault phase selection of mine power supply system based on frequency distribution theory
, 2017 In view of the problem of ineffective selection of asymmetric mine neutral point ungrounded system while high resistance grounding occurs, a fault phase selection of mine power supply system based on frequency distribution theory was proposed. Each phase
HE Ziyua, CHEN Zhihui, YU Qun
core +1 more source
Design of a Novel Mine-used Intelligent Water-pressure Sensor
Gong-kuang zidonghua, 2012 The paper introduced design schemes of whole structure, main hardware circuits and software of a novel mine-used intelligent water-pressure sensor based on STM32F103RBT6.
MIAO Juan-juan, XU Le-nia
doaj
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Design of a Soft-start Circuit for Mine-used Intrinsic Safety Device
Gong-kuang zidonghua, 2011 For problems that instantaneous large current in start of mine-used devices could lead to power supply cutting-off and abnormal start of the devices, the paper introduced design of a kind of soft-start circuit for mine-used intrinsic safety devices which
FANG Bin, SHEN Xiao-qiang, QIU Yu
doaj