Results 81 to 90 of about 452,078 (267)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Financial Risks of Investments in Coal [PDF]

open access: yes, 2011
Analyzes the regulatory, commodity, and construction risks of investing in coal mining and coal-fired power plants. Examines industry analysts' consensus on viable alternatives to coal, including natural gas, solar, wind, and energy ...
Amy Galland, Leslie Lowe, Tom Sanzillo
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Англійська мова для навчання і роботи. Т. 3. Дискусії та презентації [PDF]

open access: yes, 2013
Розглянуто всі види діяльності студентів з вивчення англійської мови, спрямовані на розвиток мовної поведінки, необхідної для ефективного спілкування в академічному та професійному середовищах.
Зуєнок, Ірина Іванівна   +3 more
core  

Economic criteria for optimizing the number and load factor of mining transformers [PDF]

open access: yes, 2019
Purpose. This article discusses how to choose the optimal number and load factor, respectively the economic power in the first year of mining power transformers operation. The analysis is carried out based on technical-economic criteria.
Deliu, F   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Unravelling the relative contributions of climate change and ground disturbance to subsurface temperature perturbations: Case studies from Tyneside, UK [PDF]

open access: yes, 2016
When assessing subsurface urban heat islands (UHIs) it is important to distinguish between localized effects of land-use change and the impacts of global climate change. However, few investigations have successfully unraveled the two influences.
Westaway, Rob, Younger, Paul L.
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Design of wide range DC input power module used in coal mine

open access: yesGong-kuang zidonghua, 2015
In view of problems that power supply voltage level and power type between mine-used sensors and DC power supply system is inconsistent, a design scheme of new type of wide range DC input and intrinsic safety type power module was put forward.
HU Yun   +3 more
doaj   +1 more source

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