Results 211 to 220 of about 10,579 (304)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Most respiratory symptoms have resolved 9 years after PM_2.5 exposure from the Hazelwood coal mine fire. [PDF]

Environ Epidemiol
Smith CL, Gao CX, O'Sullivan CF, Borg BM, Lane TJ, Brown D, Ikin J, Carroll MTC, Walker-Bone K, Thompson BR, Abramson MJ.   +10 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Study on pressure-relief effect and protection scope of long-distance lower protective seam mining based on similar physical simulation and PFC^3D. [PDF]

Sci Rep
Zhan K, Liu Z, Wei D, Yao W, Zhou W, Zhu R, Yuan Y, Yang Y, Zhang D, Li B.   +9 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Freshwater Conservation Priority Areas Are Threatened by Global Mining Activities. [PDF]

Glob Chang Biol
Braz Pires M, Baltus N, Marques A, Kleijn R, Buxton M, Maus V, Barbarossa V.   +6 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Biochemical and cellular effects of squalene on human gingival fibroblasts in an in vitro wound healing model. [PDF]

BMC Complement Med Ther
Özdemir A, Yılmaz AM, Öztürk Özener H.   +2 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Screening Bioremediation for the Effective Removal of Regulated and Emerging Contaminants from Mining Wastewater. [PDF]

Molecules
Gajendra N, Török AI, Avsar D, Pelkonen MK, Angyus SB, Grønvold RL, Tănăselia C, Levei EA, Ferrando-Climent L.   +8 more
europepmc   +1 more source