Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing +9 more
wiley +1 more source
Application of Artificial Intelligence in Predicting Coal Mine Disaster Risks: A Review. [PDF]
Lu P, Liu Y, Liang Y, Cui D.
europepmc +1 more source
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen +7 more
wiley +1 more source
Construction and application of optimized model for mine water inflow prediction based on neural network and ARIMA model. [PDF]
Gong X +11 more
europepmc +1 more source
Ciclopirox Olamine Inhibits the NLRP3 Inflammasome to Alleviate Inflammatory Diseases
There is no drug targeting the NLRP3 inflammasome that has been approved for use in clinical settings. Ciclopirox olamine (CPX), an antifungal agent approved by the US Food and Drug Administration (FDA), is identified as a specific and potent NLRP3 inflammasome inhibitor. CPX targets the NACHT domain of NLRP3 at Y381 to impair NLRP3 oligomerization and
Xinyu Xia +7 more
wiley +1 more source
PROGNOZ WATER INFLOWS OF SUBPERMAFROST WATER IN COAL MINE “UGOL’NAYA” (CHUKOTKA)
Metods of prognosis water inflows of subpermafrost waters into coal mine on Chukotka are investigated. Initial and utmost water inflows estimated on base maps “true” and generalized hydrogeological parameter.
openaire +1 more source
Investigating steeply inclined abandoned mines for unlocking the secrets of water level recovery. [PDF]
Li Y +7 more
europepmc +1 more source
Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley +1 more source
Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung +7 more
wiley +1 more source
Optimization of mine ventilation energy consumption based on improved dung beetle algorithm. [PDF]
Bingyan G, Zhe K.
europepmc +1 more source

