Results 191 to 200 of about 482,064 (252)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Mine Subsidence in Indiana [PDF]

, 1982
About 100,000 acres of southwestern Indiana are undermined, but there are no estimates of the total acreage of subsidence damage. Subsidence is indicated by the formation of sinkholes, ponds, and troughs, alteration of the flow of ground water, and ...
Harper, Denver
openaire   +2 more sources

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Vulnerability Assessment of Mining Subsidence Hazards

Risk Analysis, 2009
Between 1996 and 1999, five mining subsidence events occurred in the iron‐ore field in Lorraine, France, and damaged several hundred buildings. Because of the thousand hectares of undermined areas, an assessment of the vulnerability of buildings and land is necessary for risk management.
Deck, Olivier, Verdel, Thierry, Salmon, Romuald   +2 more
openaire   +3 more sources

Mine subsidence investigations over a longwall working and the prediction of subsidence parameters for Indian mines

International Journal of Rock Mechanics and Mining Sciences & Geomechanics Abstracts, 1973
Abstract The results of subsidence investigations over the workings of a longwall panel, above which two old workings are present, are described in this paper. These results provide a typical example of subsidence behaviour in Indian mines. The minimum area of extraction for the first subsidence to occur has been found to be considerably more than ...
R. Kumar, B. Singh
openaire   +1 more source

THE GRAVIMETRIC DETECTION OF MINING SUBSIDENCE*

Geophysical Prospecting, 1985
AbstractA series of gravity measurements were taken over a period of time (c. 150 days each) above two adjacent working coal faces. Precise levelling and gravity measurements were taken along the same profile before, during, and after seam extraction. The observed change in gravity agrees well with the levelling data.
openaire   +1 more source

Ground subsidence and mine backfill

1983
Extraction of mineral resources from the ground has caused surface subsidence and caving in many areas. Past caving problems due to underground mining have sponsored more responsible regulations, but the recognition that base minerals are depleting resources has produced a demand for higher extraction ratios with less ore left underground to support ...
openaire   +1 more source

Mining subsidence. In site investigations in areas of mining subsidence

International Journal of Rock Mechanics and Mining Sciences & Geomechanics Abstracts, 1975
openaire   +1 more source