Results 41 to 50 of about 5,090 (303)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Application of surface geophysics to detection and mapping of mine subsidence fractures in drift and bedrock

, 1995
This research was supported by a grant from the Illinois Mine Subsidence Research Program and the Department of Geology, Northern Illinois University ...
Johnston, M.A., Booth, C.J., Carpenter, P.J.   +2 more
core   +1 more source

Study on subsidence evolution induced by coal mining under highway based on finite element simulation

Energy Exploration & Exploitation
Accurate estimation of overlying strata subsidence and surface deformation caused by coal extraction is crucial for assessing the impact of mining activities on surface infrastructure.
Guoxi Cheng, Huibin Liu, Fengli Li, Teng Nie, Qiang Wang, Chuang Peng   +5 more
doaj   +1 more source

Improved Knothe surface dynamic subsidence prediction model and its parameter analysis

Yantu gongcheng xuebao, 2023
In view of the shortcomings of the traditional Knothe time model in describing the process of surface dynamic subsidence, based on the Knothe time model, considering the nonlinear mechanical characteristics of the overlying strata, an improved Knothe ...
ZHANG Liangliang 1, CHENG Hua 1, 2, YAO Zhishu 1, WANG Xiaojian 1
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Solutions to Some Mine Subsidence Research Challenges

, 2020
The objective of this work is to address three challenging topics, (1) effects of overburden key strata on subsurface subsidence; (2) effects of longwall subsidence on interstate highways and highway bridges; and (3) effects of dewatering mine water on ...
Yang, Jian
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Estimation of Deformation Intensity above a Flooded Potash Mine Near Berezniki (Perm Krai, Russia) with SAR Interferometry

Remote Sensing, 2020
In this study we used RADARSAT-2 and Sentinel-1 Synthetic Aperture Radar data for measuring subsidence above a flooded potash mine, which is almost entirely located within the city of Berezniki (Perm Krai, Russia), population 150,000.
Sergey Samsonov, Alexandr Baryakh
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

High-extraction coal mining in Illinois: Effects on crop production, 1985-1987

, 1988
This work was sponsored by the Illinois Mine Subsidence Research Program administered by the Illinois State Geological Survey through a grant from the Coal Development Board of the Illinois Department of Energy and Natural Resources and the members of
Darmody, Robert G., Carmer, S.G., Jansen, I.J., Steiner, S.J.   +3 more
core   +1 more source