Results 111 to 120 of about 28,109 (308)

The Aznalcóllar mine-tailing spill: trace elements in remediated soils [PDF]

, 2001
The Aznalcóllar mine-tailing spill (25th April 1998) affected about 2700 ha of agricultural land. Approximately 6 million cubic meters of slurry inundated both riverbanks of the Agrio and Guadiamar rivers.
Cabrera, Francisco, Moreno Lucas, Félix
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Thixotropy of unclassified pastes in the process of stirring and shearing

工程科学学报, 2016
The thixotropy of pastes is a complex rheology phenomenon,which concerns paste mixing preparation,pipeline transportation,flowing in stopes and many other aspects.
YANG Liu-hua, WANG Hong-jiang, WU Ai-xiang, XING Peng, GAO Wei-hong   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Environmental compliance assessment for the desulfurization of sulfide mine waste tailings: A case study of Ok Tedi Mine, Papua New Guinea

Environmental Challenges
The effective management of sulfide mine waste tailings is a complex task because of the potential for acid rock drainage to harm aquatic ecosystems. Although previous research has explored the environmental consequences of sulfide mine waste tailings ...
Wesley Kiwingim, Aine Gormley, Richard Douglas, Joerg Arnscheidt   +3 more
doaj   +1 more source

Evaluation of heavy metal contamination in copper mine tailing soils of Kitwe and Mufulira, Zambia, for reclamation prospects. [PDF]

Sci Rep, 2022
Dusengemungu L, Mubemba B, Gwanama C.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Effect of the Class C Fly Ash on Low-Reactive Gold Mine Tailing Geopolymers. [PDF]

Polymers (Basel), 2022
Perera-Mercado Y, Hedayat A, Tunstall L, Clements C, Hylton J, Figueroa L, Zhang N, Bolaños Sosa HG, Tupa N, Yanqui Morales I, Canahua Loza RS.   +10 more
europepmc   +1 more source

Avaliação do impacte da drenagem de água ácida na hidrogeoquímica do rio Zêzere : o caso de estudo da mina da Panasqueira, Portugal [PDF]

, 2011
A mineralização hidrotermal da Panasqueira localiza-se no centro de Portugal e é o maior depósito de Sn-W da Europa Ocidental. A exploração mineira e as operações do tratamento do minério deram origem a escombreiras de grandes dimensões, principalmente,
Candeias, Carla, Ferreira, Adelaide, Melo, Rita, Salgueiro, Ana Rita, Silva, Eduardo Ferreira da, Ávila, Paula Freire   +5 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source