Results 41 to 50 of about 860,594 (296)

Study of the Influence of Different Clothing Materials for Mine Ventilation Clothing on Human Body and Microclimate under Clothing

Sustainability, 2022
In order to study the influence of clothing materials on the cooling effect of mine ventilation clothing, the temperatures of human skin and micro-environment under clothing were used as reflection indexes of the cooling effect, and numerical simulations
Bo You, Jiao Yang, Jianfeng Liu, H. Liu, Yi Lu, Q. Han, YiXin Zhang   +6 more
semanticscholar   +1 more source

Architecture and Application of Mine Ventilation System Safety Knowledge Graph Based on Neo4j

Sustainability
To improve the safety management and accident prevention capabilities of mine ventilation systems, the application of knowledge graph technology is proposed.
Keping Zhou, Xiaohui Lu, Chun Yang, Zhiqing Chen, Wei Liu, Haiwen Yan   +5 more
semanticscholar   +1 more source

Technology of stereoscopic curtain grouting for accurate air leakage plugging and efficient fire prevention and extinguishing technology in Shendong Mining Area

Meikuang Anquan
To effectively control the hidden danger of coal spontaneous combustion caused by air leakage in shallow buried coal seam in Shendong Mining Area, taking the upper and lower coal seams of Huojitu Well 12 in Daliuta Coal Mine as the research object, the ...
Bingbing HE, Qingxiang WANG, Yayou XU, Yongning YU, Yingbing YANG, Chengmao HE, Chicheng MA, Chao XU, Jianglong WANG, Long LI, Xiaolin SONG   +10 more
doaj   +1 more source

Reliability evaluation of mine ventilation system

Gong-kuang zidonghua, 2015
Based on comprehensive analysis of factors that affect reliability of mine ventilation system, a reliability evaluation index system of coal mine ventilation system was established with 13 main factors as evaluation indexes.
ZHANG Congcong, WU Shiyue, AN Xingwei, XUE Liping, WU Qinglin   +4 more
doaj   +1 more source

Energy Consumption Reduction in Underground Mine Ventilation System: An Integrated Approach Using Mathematical and Machine Learning Models Toward Sustainable Mining

Sustainability
This study presents an integrated approach combining the Hardy Cross method and a gradient boosting (GB) optimization model to enhance ventilation systems in underground mines, with a specific application at the Jabal Sayid mine in Saudi Arabia.
Hussein A. Saleem
semanticscholar   +1 more source

Research progress and trend analysis of comprehensive prevention and control of coal spontaneous combustion throughout all stages

Meikuang Anquan
To gain a profound understanding of the current status and future trends in the comprehensive prevention and control of coal spontaneous combustion, this paper comprehensively reviews stages and research progress in the aspects of “monitoring and early ...
Yingbing YANG, Zhenqiang XING, Yunzeng ZHANG, Jiace GUO, Long LI, Wenyong LU, Minghao CHEN   +6 more
doaj   +1 more source

Identification of zones of influence of exogenous fire damaging factors [PDF]

E3S Web of Conferences, 2020
In this work, topological configuration of dangerous zone in the mine ventilation network and concentrations of fire gases in it are estimated and identified at vent impacting on the emergency conditions.
Kokoulin Ivan, Bunko Tetiana, Yashchenko Ihor, Papirnyk Ruslan, Belikov Anatolii, Myroshnychenko Vadym, Otchenashev Oleksandr   +6 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Optimization Method of Mine Ventilation Network Regulation Based on Mixed-Integer Nonlinear Programming

Mathematics
Mine ventilation is crucial for ensuring safe production in mines, as it is integral to the entire underground mining process. This study addresses the issues of high energy consumption, regulation difficulties, and unreasonable regulation schemes in ...
Lixue Wen, Deyun Zhong, Lin Bi, Liguan Wang, Yulong Liu   +4 more
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source