Results 171 to 180 of about 5,456,300 (272)

Characteristic of the infiltration recharge effect in coal mine under reservoirs. [PDF]

Sci Rep
Long T, Guo K, Shang R, Wang Q.
europepmc   +1 more source

Evaluating Climate Change Impacts on Long-Duration Snowmelt Events and Mine Water Management

Mine water management systems in northern latitude and high-elevation areas must be designed to withstand floods caused by snowmelt events (snowmelt-only and rain-on-snow) in addition to rain-only events.
Whitmore, Nicole, Liew, Michelle
core  

Hederagenin Attenuates Morphine Addiction via GABAA1‐Mediated Modulation of Ca2+–CaMK–CREB Signaling in Ventral Tegmental Dopaminergic Neurons

Advanced Science, EarlyView.
Hederagenin is identified as a GABAA1‐targeting natural compound that suppresses morphine‐associated reward by restraining Ca2+–CaMK–cAMP–CREB signaling in ventral tegmental dopaminergic neurons. RVG29‐modified liposomal delivery further enhances brain accumulation and behavioral efficacy, providing a mechanistically defined strategy for natural ...
Hongyang Jiang, Ziting Zhou, Nannan Xue, Jiasi Deng, Yuanyuan Zhou, Xinying Lv, Yuxuan Wang, Yi Zhang, Haotian Pan, Geyan Xu, Yinkun Tao, Mengran Li, Xin Cui, Hongyue Ma, Qian Wang, Zhigang Lu   +15 more
wiley   +1 more source

Identification of Discharge Pathways of Acidic Wastewater from a Bauxite Mine (Lujiang Alum Mine, China) Before and After Artificial Disturbance. [PDF]

Toxics
Wang W, Jia W, Xu L, He Z, Kang B, Chen K.   +5 more
europepmc   +1 more source

Persistent Zn2+ Influx‐Mediated Deacetylation of ANXA2 Regulates the “Zn2+‐Autophagic Flux” and Alleviates Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Zinc transporter SLC39A14 sustains intracellular Zn2+ levels to activate SIRT3‑dependent ANXA2 deacetylation at K302. This modification weakens ANXA2‑mTOR binding and releases autophagic‑flux suppression in nucleus pulposus cells. Dysregulated Zn2+ homeostasis disrupts this axis to drive intervertebral disc degeneration.
Yuxin Jin, Yongcheng Chen, Yihao Xie, Dongyang Hu, Longhui Gong, Zhihua Chen, Linjie Chen, Minhao Gao, Qizhu Chen, Morgan Jones, Hui Wang, Xiuling You, Kenny Yat Hong Kwan, Shoutao Weng, Taidong Lyu, Xiang Chen, Yuxiao Zhu, Yusheng Wang, Bin Li, Xiangyang Wang, Xiaofeng Jia, Kailiang Zhou, Ouqiang Wu, Aimin Wu   +23 more
wiley   +1 more source

VMD-LSTM based water level prediction of aquifer in mining working face. [PDF]

Sci Rep
Zhang G, Jiao B, Ji X, Chen J, Fan M, Zhao L, Zhou G.   +6 more
europepmc   +1 more source

Active Oscillations of Elastic Membranes Arising from the Coupling with a Catalytic Reaction

Advanced Science, EarlyView.
Coupling an elastic membrane to a catalytic reaction produces active oscillations that self‐sustain for hours: the membrane cyclically inflates and deflates as the reaction spontaneously activates and deactivates, without external power. Energy release is directly embodied in the oscillation dynamics, opening elasto‐chemical strategies for the physical
Alberto Comoretto, Samuel D. Gollob, Erik Steur, Kaitlyn P. Becker, Ellen T. Roche, Johannes T.B. Overvelde   +5 more
wiley   +1 more source

Integration of Multiframe and Multichannel Residual Attention Models for Mine Water Hazard Video Feature Recognition. [PDF]

ACS Omega
Zhang S, Liu Y, Wang C, Wei Y, Luo H, Sheng H, Du Y, Wang R, Wu Z, Liu J.   +9 more
europepmc   +1 more source

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

Evaluation of Grouting Reinforcement Effectiveness in Coal Seam Floors Using the Monte Carlo Analytical Hierarchy Process: A Case Study of the Rongkang Coal Mine. [PDF]

ACS Omega
Gao C, Ma J, Wang D, Wang L, Yang X, Ren Y, Yang J, Xu W, Chen Z.   +8 more
europepmc   +1 more source