Results 101 to 110 of about 47,585 (287)

Investigation on mineral and bone abnormalities in 123 maintenance hemodialysis patients

Linchuang shenzangbing zazhi, 2018
Objective To investigate and analyze the controlling situation of mineral and bone disorder(MBD) in maintenance hemodialysis patients, analyze their related factors, and discuss control methods. Methods We investigated MBD in 123 maintenance hemodialysis
LAN Tian-ying, YE Chao-yang, YAO Dong-sheng, WU Feng, WANG Luo-bin, WANG Chen   +5 more
doaj  

LP533401 treatment alters vitamin K metabolism, bone Gla-OC/Glu-OC ratios, and improves mineral status of the skeleton in rats with chronic kidney disease

Frontiers in Pharmacology
BackgroundChronic kidney disease-mineral and bone disorder (CKD-MBD) is associated with impaired bone mineralization and vitamin K (VK) deficiency. Peripheral serotonin (5-HT) adversely affects bone integrity, but its relationship with VK metabolism ...
Magdalena Kopańko, Beata Sieklucka, Dariusz Pawlak, Magdalena Zabłudowska, Katarzyna Sokołowska, Urszula Łebkowska, Krystyna Pawlak   +6 more
doaj   +1 more source

Mineral and bone disorder in Chinese dialysis patients: a multicenter study

BMC Nephrology, 2012
Background Mineral and bone disorder (MBD) in patients with chronic kidney disease is associated with increased morbidity and mortality. Studies regarding the status of MBD treatment in developing countries, especially in Chinese dialysis patients are ...
Kong Xianglei, Zhang Luxia, Zhang Ling, Chen Nan, Gu Yong, Yu Xueqing, Liu Wenhu, Chen Jianghua, Peng Liren, Yuan Weijie, Wu Hua, Chen Wei, Fan Minhua, He Liqun, Ding Feng, Chen Xiangmei, Xiong Zuying, Zhang Jinyuan, Jia Qiang, Shi Wei, Xing Changying, Tang Xiaoling, Hou Fanfan, Shu Guiyang, Mei Changlin, Wang Li, Xu Dongmei, Ni Zhaohui, Zuo Li, Wang Mei, Wang Haiyan   +30 more
doaj   +1 more source

Skeletal effects and growth in children with chronic kidney disease: a 5-year prospective study

, 2013
This study was designed to follow the evolving process of growth, bone modeling and remodeling in children with chronic kidney disease (CKD) who are at risk of developing CKD-mineral bone disorder (CKD-MBD).
Hansson, Sverker,, Magnusson, Per, Swolin-Eide, Diana,, Magnusson, Per,   +3 more
core   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Mineral and bone disorder of maintenance hemodialysis patients in Chuzhou

Linchuang shenzangbing zazhi, 2016
Objective To understand the mineral and bone disorder(MBD) status of the maintenance hemodialysis(MHD) patients in Chuzhou.Methods The MHD patients were investigated in hemodialysis centers of 7 hospitals in Chuzhou from April 2014 to June 2014.Study ...
XU Qi, YE Li-ping, CHENG Wei, GAO Lu, SUN Ai-hua, GAO Ye-hu, LIN Li, CHEN Tian-hao, YAO Yin-ping, YAO Yong   +9 more
doaj  

Thyrotoxic periodic paralysis with bone metabolism disruption: a case report

Journal of the Pakistan Medical Association
Thyrotoxic Periodic Paralysis (TPP) is a rare condition associated with hyperthyroidism, particularly in young males. This report presents the case of a 20-year-old male with TPP complicated by decreased bone mineral density (BMD).
Longying Wang, Dong Luo, Dalian Wang, Ping Li, Yan Liu, Zhilong Liu   +5 more
doaj   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

U-Net-Based Deep Learning Hybrid Model: Research and Evaluation for Precise Prediction of Spinal Bone Density on Abdominal Radiographs

Bioengineering
Osteoporosis is a metabolic bone disorder characterized by the progressive loss of bone mass, which significantly increases the risk of fractures. While dual-energy X-ray absorptiometry is the standard technique for assessing bone mineral density, its ...
Lixiao Zhou, Thongphi Nguyen, Sunghoon Choi, Jonghun Yoon   +3 more
doaj   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source