Results 51 to 60 of about 47,585 (287)

Unique Role of Microstructure of a Bioimplant Zinc Alloy and Protein Content of Simulated Body Fluid in Corrosion and Fracture

Advanced Functional Materials, EarlyView.
BSA addition to physiological solutions enhances resistance of a Zn alloy to stress corrosion cracking (SCC) but reduces its corrosion resistance. Extended surface characterization explains the contrasting influences on corrosion and SCC. Unexpectedly, the alloy suffers transgranular SCC (TGSCC), despite extensive grain boundary precipitation. Thorough
RK Singh Raman, Syed Hussain Wajahat, Saad Al‐Saadi, Robin E. Schäublin, Peng Zeng, Solomon Ansah, Jixing Lin, Xian Tong, Cuie Wen, Jörg F. Löffler   +9 more
wiley   +1 more source

Mineral bone disorders in chronic kidney disease [PDF]

Nephrology, 2018
ABSTRACT As the GFR loss aggravates, the disturbed mineral metabolism worsens the bone microstructure and remodelling ‐ scenario, which is known as CKD‐mineral bone disease (MBD). CKD‐MBD is characterized by : (i) abnormal metabolism of calcium, phosphorus, parathyroid hormone (PTH), or vitamin D; (ii) abnormalities in bone turnover ...
Yi-Chou, Hou, Chien-Lin, Lu, Kuo-Cheng, Lu   +2 more
openaire   +2 more sources

Dynamic Observation of Lacy Pattern Formation in a Bone Tissue Model Using Liquid Phase Scanning Transmission Electron Microscopy

Advanced Functional Materials, EarlyView.
Here, we establish a low‐dose liquid‐phase electron microscopy workflow for real‐time observation of biological processes in hydrated conditions. Beam damage is reduced by imaging only 20% of the pixels and reconstructing the complete image using an inpainting algorithm.
Luco Rutten, Avital Wagner, Rona Roverts, Luco Buise, Ben Joosten, Anat Akiva, Elena Macías‐Sánchez, Nico Sommerdijk   +7 more
wiley   +1 more source

Chronic kidney disease-mineral and bone disorder

, 2018
The kidneys play a critical role in maintaining normal serum calcium and phosphorus concentrations, under the regulation of three main hormones: parathyroid hormone, calcitriol, and fibroblast growth factor 23.
Menaka Sarav, Stuart M. Sprague
core   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

Advanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu, Mahboobeh Mahmoodi, Ehsanul Hoque Apu, Fahimeh Shahabipour, Sibel Emir Diltemiz, Sanjib Saha, Halima Alem, Nureddin Ashammakhi   +7 more
wiley   +1 more source

Effect of Advanced Glycation End‐Products (AGE) Lowering Drug ALT‐711 on Biochemical, Vascular, and Bone Parameters in a Rat Model of CKD‐MBD

, 2019
Chronic kidney disease–mineral bone disorder (CKD‐MBD) is a systemic disorder that affects blood measures of bone and mineral homeostasis, vascular calcification, and bone.
Nickolas, Thomas L., Avin, Keith G., Keith G Avin, O'Neill, Kalisha, Thomas L Nickolas, Corinne E Metzger, Metzger, Corinne E., Joseph M Wallace, Srinivasan, Shruthi, Shruthi Srinivasan, Creecy, Amy, Amy Creecy, Allen, Matthew R., Sharon M Moe, Moe, Sharon M., Wallace, Joseph M., Matthew R Allen, Neal X Chen, Kalisha O'Neill, Chen, Neal X.   +19 more
core   +1 more source

Gaucher Disease in Bone: From Pathophysiology to Practice [PDF]

, 2019
Gaucher disease (GD) is a rare, genetic lysosomal disorder leading to lipid accumulation and dysfunction in multiple organs. Involvement of the skeleton is one of the most prevalent aspects of GD and a major cause of pain, disability, and reduced quality
Peter Mikosch, Hughes D., Francesca Carubbi, Cox, Timothy M.,, Kindmark A., Mikosch, Peter, Hughes, Derralynn, Mistry P., Ludger Poll, Poll, L, Nadia Belmatoug, Mikosch, P, Deegan, Patrick,, Belmatoug N., Andreas Kindmark, Weinreb N., Deegan P., Cox T., Kindmark, A, PramodK Mistry, Hughes, Derralynn,, Goker-Alpan, Ozlem,, Weinreb, Neal, Poll L., Weinreb, N, Mistry, PramodK, Poll, Ludger, Carubbi, Francesca,, Belmatoug, N, Deegan, P, Poll, Ludger,, TimothyM Cox, Hughes, D, Derralynn Hughes, Belmatoug, Nadia,, Mikosch, Peter,, Weinreb, Neal,, Cox, T, Deegan, Patrick, Belmatoug, Nadia, Ozlem Goker‐Alpan, Patrick Deegan, Mistry, PramodK,, Kindmark, Andreas, Cox, Timothy M., Kindmark, Andreas,, Goker-Alpan O., Mistry, P, Carubbi F., Goker-Alpan, Ozlem, Neal Weinreb, Goker-Alpan, O, Carubbi, Francesca, Carubbi, F, Mikosch P.   +54 more
core   +1 more source

Developments in rare bone diseases and mineral disorders [PDF]

Therapeutic Advances in Chronic Disease, 2017
In the last decade, there have been a number of significant advances made in the field of rare bone diseases. In this review, we discuss the expansion of the classification system for osteogenesis imperfecta (OI) and the resultant increase in therapeutic options available for management of OI.
Siobhan, Bacon, Rachel, Crowley
openaire   +2 more sources

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Advanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu, Ruo‐xin Wang, Feng He, Qian Liu, Fu‐yin Li, Min Hui, Yu‐qian Shi, Yu Jiang, Qing‐hua Li, Jun‐wen Jing, Shi‐bin Yu, Li‐tian Ma, Qian‐nan Niu, Mian Zhang   +13 more
wiley   +1 more source