Results 221 to 230 of about 2,538,610 (251)

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

A Possible Case of Temporomandibular Joint Dislocation, Trepanation, and Metabolic Bone Disease in a Young Adolescent From North‐Central Myanmar (1000–700 bce)

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT This osteobiography explores the life history of an adolescent who lived during the early‐mid Bronze Age (c. 1000–700 bce) and was buried at Nyaung'gan, a site in north‐central Myanmar. Burial 3b had multiple skeletal lesions, and their bones were covered in well‐remodeled subperiosteal new bone.
Anna Willis, Baptiste Pradier, Thu Thu Win, T. O. Pryce   +3 more
wiley   +1 more source

Bone Adaptation and Labor Organization in Co‐Located Medieval Anatolian Populations

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT Skeletal evidence from geographically co‐located populations offers a rare opportunity to disentangle subsistence‐driven bone adaptation from socially organized labor. This study examines upper limb morphology in two Byzantine communities—the urban center of Tyana (10th–13th c.
Gökhan Çakan, Ahmet G. Erdemir, Adalet E. Yıldız, Üstün Aydıngöz, Osman Doğanay, Ömür Dilek Erdal   +5 more
wiley   +1 more source

Current Trends and Future Prospects of Integrating Electrospinning With 3D Printing Techniques for Mimicking Bone Extracellular Matrix Scaffolds

Journal of Polymer Science, Volume 63, Issue 6, Page 1481-1504, 15 March 2025.
ABSTRACT This article presents a review of the recent findings on the combination of electrospun nanofibers and three‐dimensional (3D)‐printed structures for extracellular matrix (ECM) scaffolds for bone tissue engineering. We explore the synergy between electrospinning (ES), which produces highly porous, fibrous structures from materials like collagen
Kardo Khalid Abdullah, Kolos Molnár
wiley   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Association Between Mineral Metabolism Abnormalities and Vascular Access Complications Among Maintenance Hemodialysis Patients in Ethiopia. [PDF]

Int J Nephrol
Bekele DR, Gebregiorgis TB, Guji AA, Tukeni KN.   +3 more
europepmc   +1 more source

Endocrine-related osteoporosis: bone quality, clinical phenotype, and targeted management. [PDF]

Front Endocrinol (Lausanne)
Cincione IR, Marcantonio R, Monda M, Polito R, Casillo M, Messina A, Monda A, Moscatelli F, Messina G, Panico A.   +9 more
europepmc   +1 more source