Results 51 to 60 of about 4,004,971 (303)

Combined application of computational fluid dynamics (CFD) and design of experiments (DOE) to hydrodynamic simulation of a coal classifier [PDF]

open access: yesInternational Journal of Mining and Geo-Engineering, 2017
Combining the computational fluid dynamics (CFD) and the design of experiments (DOE) methods, as a mixed approach in modeling was proposed so that to simultaneously benefit from the advantages of both modeling methods.
Hamid Khoshdast   +2 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Preparation of a Master Fe–Cu Alloy by Smelting of a Cu-Bearing Direct Reduction Iron Powder

open access: yesMetals, 2019
Generally, the Cu-bearing direct reduction iron powder (CBDRI) obtained from a direct reduction-magnetic separation process of waste copper slag contains a high content of impurities and cannot be directly used to produce Cu-bearing special steel.
Liaoting Pan   +3 more
doaj   +1 more source

Thermodynamic and Experimental Substantiation of the Possibility of Formation and Extraction of Organometallic Compounds as Indicators of Deep Naphthogenesis

open access: yesEnergies, 2023
In this article, typomorphic associations of microelements in carbonaceous caustobioliths and oils are defined as indicators of naphthogenesis based on the analytical survey of the literature and our own research.
Tatiana Aleksandrova   +2 more
doaj   +1 more source

[Annexin in mineralization process].

open access: yesPostepy biochemii, 2007
Annexins are necessary for mineralization process. They seem to play a major role in regulation of cells competent in mineralization as well as in direct formation of mineral phase in the extracellular matrix. Their ability to accommodate to different functions in different cellular compartments is associated with their property to bind to biological ...
Anna Sekrecka-Belniak   +4 more
openaire   +1 more source

GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors

open access: yesFEBS Open Bio, EarlyView.
GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille   +6 more
wiley   +1 more source

On the Challenges of Applying Machine Learning in Mineral Processing and Extractive Metallurgy

open access: yes, 2023
The application of Machine Learning in Mineral Processing and Extractive Metallurgy has important benefits in terms of increasing the predictability and controllability of the processes, optimizing their performance, and improving maintenance.
Pía Lois-Morales   +3 more
core   +1 more source

Synchronous Upgrading Iron and Phosphorus Removal from High Phosphorus Oolitic Hematite Ore by High Temperature Flash Reduction

open access: yesMetals, 2016
In this paper, an effective method was developed to remove phosphorus and upgrade iron from high phosphorus oolitic hematite ore by high temperature flash reduction—a wet magnetic separation process.
Deqing Zhu   +3 more
doaj   +1 more source

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