Results 121 to 130 of about 104,435 (265)

The Fragile Sink: Reconceptualizing Soil Carbon Stabilization and Its Vulnerability Under Global Change. [PDF]

Glob Chang Biol
Iqbal MM, Farooq MA, Lal R, Abdalla M, Smith P.   +4 more
europepmc   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Multifunctional Dyeing of Textiles with Turmeric (<i>Curcuma longa</i> L.) Extracts Using Natural Mordants. [PDF]

Molecules
Yang R, Li C, Zheng Y, Huang C, Yao R, Li J, Inta A, Yang L.   +7 more
europepmc   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

Global Change Impacts on Mineral-Associated Organic Matter: Consequences for Soil Carbon Persistence. [PDF]

Glob Chang Biol
Jia J, Feng X.
europepmc   +1 more source

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

Advanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu, Xuan Lu, Yuquan Wang, Haihua Ji, Ying Zhang, Yiqun Wan, Hao Wan   +6 more
wiley   +1 more source

Rice Cultivation Duration Drives Soil Organic Carbon Stabilization in Saline-Alkaline Paddy Soils via Mineral-Associated Organic Carbon Accumulation and Biological Pathways. [PDF]

Biology (Basel)
Xu F, Wang M, Lu Z, Xie Y, Tian L, Lv C, Zhang X, Song Y, Yao X, Zhang H, Zhang D.   +10 more
europepmc   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Declines in organic matter persistence with increased soil carbon. [PDF]

Nat Commun
Zhao G, Liang C, Liu Z, Cong N, Zheng Z, Bai E, Zhu J, Zhao B, Zhu Y, Cai M, Duan X, Wang H, Huang J, Zhang Y, Trumbore S.   +14 more
europepmc   +1 more source

Mineral Metabolism: Phosphonates to protect Bone [PDF]

Nature, 1969
openaire   +1 more source