Results 211 to 220 of about 61,117 (342)

A Novel SCNN1B Mutation in a Neonate With Systemic Pseudohypoaldosteronism Type 1: Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Early recognition of PHA1B in neonates with persistent hyperkalemia and hyponatremia is important for timely intervention. Genetic testing confirms the diagnosis, guiding long‐term management. This case highlights a novel SCNN1B mutation, expanding the genetic spectrum and emphasizing the need for lifelong monitoring to prevent life ...
Ensiyeh Bahadoran, Fatemeh Saffari, Sahar Moghbelinejad   +2 more
wiley   +1 more source

FRI162 Ligand-dependent Photocrosslinking of Mineralocorticoid Receptors Using Site-directed Incorporation of Unnatural Amino Acids

, 2023
Brian Almeida‐Prieto, Alberto J. Gonzalez-Hernandez, Teresa Giráldez, Diego Álvarez de la Rosa   +3 more
openalex   +1 more source

Edible Seeds in the Fight Against Hypertension: A Review of In Vitro, In Vivo, and Clinical Evidences With a Mechanistic Insight of Bioactive Compounds

Food Frontiers, Volume 7, Issue 1, January 2026.
The presented review provides the potential antihypertensive benefits of traditionally employed edible seeds, presenting new perspectives and avenues for future research. ABSTRACT Hypertension, often referred to as a silent killer, is responsible for 7.5 million deaths, representing approximately 12.8% of all global mortality.
Jinmin Shi, Mohamad Fawzi Mahomoodally, Ahmed Abduljalal Abduljabbar, Ruttun Bushra Umme Zainab, Katharigatta N. Venugopala, Gokhan Zengin, Sakina Yagi, Meng‐Yao Li, Xuebo Hu   +8 more
wiley   +1 more source

Mineralocorticoid receptor antagonists promote renal immunosenescence. [PDF]

Int Urol Nephrol
Wang QR, Yang Y.
europepmc   +1 more source

From Synaptic Plasticity and Critical Periods to Social Behavior and Stress: Getting to, and Staying in, CA2

Hippocampus, Volume 36, Issue 1, January 2026.
ABSTRACT Hippocampal Area CA2, with some exceptions, had long been neglected in in vivo studies, due largely to its small size, and in in vitro studies because of its general similarity to CA3 and CA1. Increasing evidence showing that CA2 was molecularly distinct led to the increased appreciation of CA2 as a separate region, and as such, that it likely
Serena M. Dudek
wiley   +1 more source

Deficiency of mineralocorticoid receptor signalling in myeloid cells protects cardiac and kidney function in hypertensive diabetic mice. [PDF]

Clin Sci (Lond)
Tesch GH, Ozols E, Morgan J, Young MJ, Nikolic-Paterson DJ.   +4 more
europepmc   +1 more source

Mineralocorticoid Receptors [PDF]

Circulation Research, 2020
openaire   +3 more sources

Evaluation of the Pharmacokinetics, Disposition, and Metabolism of Miricorilant, a Novel Glucocorticoid Receptor Modulator for the Treatment of Metabolic Dysfunction‐Associated Steatohepatitis in Nonclinical and Clinical Studies

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Miricorilant is a novel selective glucocorticoid receptor (GR) modulator with mixed agonist/antagonist effects at the GR and modest antagonism at the mineralocorticoid receptor that is being developed for the treatment of metabolic dysfunction‐associated steatohepatitis.
Hazel J. Hunt, Kirsteen M. Donaldson, Jeevan R. Kunta, Joseph M. Custodio   +3 more
wiley   +1 more source

Intercellular communication from myotubes to fibroblasts is differentially impacted by mineralocorticoid receptor signaling and muscular dystrophy. [PDF]

Cell Commun Signal
Krishna S, Gomatam CK, Reddy R, Lowe J, Lepper C, Rafael-Fortney JA.   +5 more
europepmc   +1 more source

Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates Diabetic Nephropathy via suppressing SLC7A11-mediated ferroptosis [PDF]

卢 Yu, 齐汉 zhai, 尤林 王, 刘伟 王, 邱红 利, 燕红 郭, 荣 gou, 林 唐   +7 more
openalex   +1 more source