Results 221 to 230 of about 61,117 (342)

Case Report: Compound Heterozygous SCNN1B Mutations Causing Pseudohypoaldosteronism Type 1B2 in Neonatal Twins

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
First Chinese neonatal cases of systemic PHA1B from novel compound‐heterozygous SCNN1B variants (c.585+2T>C; c.1544T>C) presented with life‐threatening hyperkalemia and hyponatremia unresponsive to steroids. Early genetic testing enabled targeted sodium supplementation and potassium‐binding therapy, normalizing electrolytes and underscoring SCNN1B ...
Zhiping Wang, Lijuan Long, Hongjuan Bi
wiley   +1 more source

Real-world effectiveness of mineralocorticoid receptor antagonists in heart failure with reduced ejection fraction: a retrospective, non-interventional cohort analysis

Michael Fu, Aldina Pivodic
openalex   +1 more source

Effect of Genetic and Nongenetic Factors on the Clinical Response to Mineralocorticoid Receptor Antagonist Therapy in Egyptians with Heart Failure [PDF]

, 2019
Neven Sarhan, Mohamed H. Shahin, Nihal M. El Rouby, Lamia El Wakeel, Mohamed H. Solayman, Taimour Langaee, Hazem Khorshid, Mona F. Schaalan, Nagwa A. Sabri, Larisa H. Cavallari   +9 more
openalex   +1 more source

Association of an Algorithm‐Generated Medication Optimization Score With Clinical Outcomes in Ambulatory Patients With Heart Failure

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 1, January 2026.
ABSTRACT Aims Guideline‐directed medical therapy (GDMT) implementation in heart failure with reduced ejection fraction (HFrEF) remains suboptimal. A computable algorithm was developed to generate a medication optimization score (MOS) and provide guideline‐based recommendations.
Mohamed S. Ali, Kaitlyn M. Greer, Sabah Ganai, Todd M. Koelling, Scott L. Hummel, Michael P. Dorsch   +5 more
wiley   +1 more source

Cardiovascular-Kidney-Metabolic Effects: Steroidal and Nonsteroidal Mineralocorticoid Receptor Antagonists. [PDF]

Rev Cardiovasc Med
Bozkurt B, Januzzi JL, Bansal S.
europepmc   +1 more source

Urinary Peptidomic Profiling In Post‐Acute Sequelae of SARS‐CoV‐2 Infection: A Case‐Control Study

PROTEOMICS, Volume 26, Issue 1, Page 32-43, January 2026.
ABSTRACT Post‐acute sequelae of severe acute respiratory syndrome coronavirus 2‐infection (PASC) is challenging to diagnose and treat, and its molecular pathophysiology remains unclear. Urinary peptidomics can provide valuable information on urine peptides that may enable improved and specified PASC diagnosis.
Dilara Gülmez, Justyna Siwy, Katharina Kurz, Ralph Wendt, Miroslaw Banasik, Björn Peters, Emmanuel Dudoignon, Francois Depret, Mercedes Salgueira, Elena Nowacki, Amelie Kurnikowski, Sebastian Mussnig, Simon Krenn, Samuel Gonos, Judith Löffler‐Ragg, Günter Weiss, Harald Mischak, Manfred Hecking, Eva Schernhammer, Joachim Beige, UriCoV Working Group   +20 more
wiley   +1 more source

The mineralocorticoid receptor antagonist finerenone enhances cardiovascular recovery upon food intake normalization in obese mice. [PDF]

Cardiovasc Diabetol
Manon MF, Marie PD, Benjamin B, Coralie F, Linghui K, Amhrae ND, Lionel N, Saïda M, Sylvanie R, Anaïs D, Vincent R, Bruno F, Frédéric J, Sheerazed B, Paul M, Antoine OP.   +15 more
europepmc   +1 more source

Alcohol and the endocrine system: A critical review of disruptions, potential mechanisms, and health implications

Alcohol, Clinical and Experimental Research, Volume 50, Issue 1, January 2026.
The endocrine system coordinates whole body cellular function and maintains homeostasis. Alcohol impacts the integrity of endocrine regulation at multiple sites, contributing to risk for comorbidities. Some of the alcohol‐mediated pathophysiological effects on the endocrine system include alterations in receptor expression and responsiveness, protein ...
Patricia E. Molina, Liz Simon
wiley   +1 more source

Nonsteroidal Versus Steroidal Mineralocorticoid Receptor Antagonists in Heart Failure: Real-World Evidence From a Multicenter Cohort Study. [PDF]

J Am Heart Assoc
Wu JY, Tseng KJ, Lin YM.
europepmc   +1 more source

Overactivation of the Aldosterone^|^frasl;Mineralocorticoid Receptor System in Metabolic Syndrome and its Implication in Cardiac and Kidney Injury

, 2012
Miki Nagase
openalex   +2 more sources