Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi +11 more
wiley +1 more source
Fe(III)-(II) Mineral Transformation and Associated Organic Matter Stabilization Processes in a Tidal Marsh Soil. [PDF]
Jagode J +10 more
europepmc +1 more source
Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan +5 more
wiley +1 more source
Soil-Plant-Animal Mineral Dynamics in Extensive Goat Production Systems: A Critical Review of Geochemical Availability, Soil-Plant Transfer, and Ruminal Bioavailability. [PDF]
Rivera-Larraga JE +7 more
europepmc +1 more source
The sunscreen‐inspired nano‐pesticide, MCB@URFSL, provides UV‐shielding, enhanced rainfastness, and laccase‐responsive delivery for improved fungicidal efficacy and high ecological safety. ABSTRACT Fungicides are a crucial tool for protecting crops and ensuring consistent food supply.
Jin Yan +10 more
wiley +1 more source
Partial substitution of organic trace minerals in sow diets over multiple parities and the impact on claw health, productivity, and longevity. [PDF]
Pierdon MK, Parsons TD.
europepmc +1 more source
Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang +10 more
wiley +1 more source
Geochemical Characteristics and Influencing Factors of Germanium in Early Permian Coal from the Southern Margin of the North China Craton Basin: Constraints from Coal Petrology, Mineralogy, and Germanium Isotopes. [PDF]
Zhao S +5 more
europepmc +1 more source
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang +6 more
wiley +1 more source

