Results 161 to 170 of about 527,049 (245)

Clinical Management of Worn Ball Abutments in Mandibular Mini-Implant Overdentures: A Case Report in a Skeletal Class II Patient. [PDF]

Dent J (Basel)
Murariu-Măgureanu C, Preoteasa E, Teodorescu C, Preoteasa CT.   +3 more
europepmc   +1 more source

Loss of CYLD on Chromosome 16q Impairs Homologous Recombination and Genomic Stability Through TIRR Degradation

Advanced Science, EarlyView.
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu, Jialu Kang, Qi Ye, Zixi Wang, Lei Li, Yuzeshi Lei, Leihong Ye, Tianjie Liu, Bin Wang, Tao Liu, Shan Xu, Ke Wang, Yong Zhang, Jian Ma, Lei Li   +14 more
wiley   +1 more source

Evaluation of hard palate bone thickness on cone -beam computed tomographs for orthodontic mini-implant placement: A cross-sectional study. [PDF]

J Clin Exp Dent
Huaynate-Cuadrado S, Chávez-Sevillano MG, Blanco-Victorio D, Palomino-Gomez SP, Arieta-Miranda J, Abdo Quintão CC, Pérez-Vargas LF.   +6 more
europepmc   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Mini-Implant Rejection Rate in Teenage Patients Depending on Insertion Site: A Retrospective Study. [PDF]

J Clin Med, 2022
Bungău TC, Vaida LL, Moca AE, Ciavoi G, Iurcov R, Romanul IM, Buhaș CL.   +6 more
europepmc   +1 more source

Treatment outcomes of 3D-printed custom and conventional mini-implant assisted rapid palatal expanders (MARPE). [PDF]

Prog Orthod
Sharma Y, Suh H, Bianchi J, Yoon A, Oh H.   +4 more
europepmc   +1 more source

How Does Orthodontic Mini-Implant Thread Minidesign Influence the Stability?-Systematic Review with Meta-Analysis. [PDF]

J Clin Med, 2022
Jedliński M, Janiszewska-Olszowska J, Mazur M, Grocholewicz K, Suárez Suquía P, Suárez Quintanilla D.   +5 more
europepmc   +1 more source

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

Advanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang, Hui Wang, Hao Zhang, Zhenkuan Cao, Zehui Liu, Siying Li, Hongda Wang, Yuping Shan   +7 more
wiley   +1 more source

Evaluation of Computer-Aided Navigation and Augmented Reality for Bicortical Mini-Implant Placement in Maxillary Expansion: An In Vitro Study. [PDF]

Bioengineering (Basel)
Giovannini Riso G, Flores-Fraile J, Perrone G, Tzironi G, Galindo ABL, Galletti C, Zubizarreta-Macho Á.   +6 more
europepmc   +1 more source