Results 41 to 50 of about 485,103 (237)

In vitro In vitro evaluation of torsional strength of evaluation of torsional strength of evaluation of torsional strength of orthodontic mini-implants

open access: yesBrazilian Journal of Oral Sciences, 2016
Aim: The aim of this study was to assess the maximum torsional strength of orthodontic mini-implants of different diameters. Methods: Eighteen mini-implants measuring 10 mm in length were divided into three groups (n = 6).
Matheus Melo Pithon   +5 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Análise histomorfológica e histomorfométrica de mini-implantes para ancoragem ortodôntica imediata e precose [PDF]

open access: yes, 2005
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde . Programa de Pós-Graduação em Odontologia.O objetivo do presente estudo foi avaliar a taxa de sobrevivência e a resposta óssea de mini-implantes submetidos a forças ...
Freire, José Nilo de Oliveira
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Skeletal anchorage for tooth movements: mini implants vs osseointegrated implants

open access: yes, 2014
Background: The mini-implants are very important for preventing dental, periodontal, esthetical and psychological problems during the combined implant-orthodontic treatment.
R. Soldo   +3 more
core   +2 more sources

Miniscrew-assisted rapid palatal expansion (MARPE): Factors influencing planning [PDF]

open access: yesDental Press Journal of Orthodontics
Objective: This cross-sectional study evaluated the bone thickness on mini-implants insertion site, the factors that influence the digital planning of MARPE appliance (miniscrew-assisted rapid palatal expansion), and its different designs.
Cristiane Barros ANDRÉ   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

O uso de mini-implantes como ancoragem ortodôntica [PDF]

open access: yes, 2011
TCC (graduação) - Universidade Federal de Santa Catarina, Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Curso de Odontologia.A ancoragem ortodôntica é decisiva para o sucesso do tratamento ortodôntico, onde dispositivos intra e ...
Schlickmann, Sérgio
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

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