Results 131 to 140 of about 9,442 (158)

Optimizing recombinant mini proinsulin production via response surface method and microbioreactor screening. [PDF]

PLoS One
Ayan E, Aytekin AÖ, Kati A, Demirci H.
europepmc   +1 more source

Coastal evolution, environmental change and carbon storage in the Thung Prong Thong Mangrove, eastern Gulf of Thailand

Boreas, EarlyView.
Palaeoenvironmental records along the eastern coast of Thailand remain sparse, with only a few studies attempting to reconstruct past climatic and environmental conditions. However, additional palaeoenvironmental, palaeoclimatic and sea‐level records are needed to improve our understanding of coastal evolution and local environmental changes.
Sakonvan Chawchai, Smith Leknettip, Naomi Seaton, Kannika Wangritthikraikul, Nathalie Dubois, Ludvig Löwemark, Pei‐Ling Wang, Frank Preusser   +7 more
wiley   +1 more source

Impact of Autoclaving on the Dimensional Stability of 3D-Printed Guides for Orthodontic Mini-Implant Insertion - An In Vitro Study. [PDF]

Clin Exp Dent Res
David S, Hüfner M, Rauch N, Kerberger R, Drescher D, Brunello G, Becker K.   +6 more
europepmc   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

Brain Pathology, EarlyView.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown, Jeanne K. Brooks, Louise Kelly, Madeline M. Vroom, Matthew Longo, Jean‐Cosme Dodart, Roxana Carare, Justin D. Boyd   +7 more
wiley   +1 more source

Exploring mutual aid-based community engagement during the COVID-19 pandemic: a case study of community group buying in China. [PDF]

Front Public Health
Li W, Yu Z.
europepmc   +1 more source

Evidence of emerging transcriptome mediators of Alzheimer's disease in canine cognitive dysfunction

Brain Pathology, EarlyView.
Canine cognitive dysfunction (CCD) may be a promising model of Alzheimer's disease (AD). To assess AD‐related molecular signatures in CCD, we generated transcriptome data on dog cortex and plasma extracellular vesicles (EVs). CCD‐related transcriptome changes were similar to those in aging/AD humans and were detectable in EVs from the same animals ...
Shelby C. Osburn, Darby S. Easterday, Cali M. McEntee, Amanda S. Latham, Daniel S. Lark, Stephanie McGrath, Julie A. Moreno, Thomas J. LaRocca   +7 more
wiley   +1 more source

The emerging role of biomaterial applications in cerebral lymphatic surgical interventions: A narrative review. [PDF]

Biomater Biosyst
Jessup M, Iglesias NJ, Tadisina KK, Xu K, Mella-Catinchi J, Pinchuk L, Singh D, Tse DT, Nayak VV, Coelho PG.   +9 more
europepmc   +1 more source

A PK/PD study on antihyperalgesia by an α2/3‐GABAA receptor PAM in mice: Lack of tolerance liability and potential involvement of γ1‐GABAA receptors

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann, Mariana O. Popa, Karen T. Elvers, Misa Oyama, Daniel Ulrich, Marcus Hanley, Gui Jie Feng, Thomas Hathaway, William T. Ralvenius, Thomas Grampp, Dietmar Benke, John R. Atack, Hanns Ulrich Zeilhofer   +12 more
wiley   +1 more source

β3‐adrenoceptor agonism exerts lung protection in a rat model of bronchopulmonary dysplasia

British Journal of Pharmacology, EarlyView.
The β3‐adrenoceptors agonist BRL37344 promotes lung maturation, preventing the progression of experimental bronchopulmonary dysplasia. Absract Background and Purpose Bronchopulmonary dysplasia (BPD) affects premature newborns, particularly those receiving supplemental oxygen therapy.
Alessandro Pini, Patrizia Nardini, Virginia Zizi, Marta Molino, Maura Calvani, Francesco Carrozzo, Rachele Amato, Daniele Guasti, Denise Biagini, Fabio di Francesco, Ludovico Silvestri, Alessandra Franceschini, Daniele Bani, Elisa Imbimbo, Luca Filippi   +14 more
wiley   +1 more source

Enhanced water treatment via combined oxidation and adsorption: a synergistic approach. [PDF]

Front Chem
Shulin P, Tahri W, Khaskhoussi A, El-Sappah AH.   +3 more
europepmc   +1 more source