Results 61 to 70 of about 11,184,067 (229)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The cost-effectiveness of exercise referral schemes [PDF]

, 2011
This article is made available through the Brunel Open Access Publishing Fund - Copyright @ 2011 Anokye et al.Background: Exercise referral schemes (ERS) aim to identify inactive adults in the primary care setting.
Paul Trueman, Hillsdon, M, Nana K Anokye, Anokye, Nana K, Pavey, TG, Green, C, Colin Green, Pavey, Toby G, Anokye, Nana K., Taylor, RS, Green, Colin, Hillsdon Melvyn, Taylor, Rod S., Melvyn Hillsdon, Pavey, Toby G., Trueman, P, Toby G Pavey, Anokye Nana K, Green Colin, Anokye, NK, Trueman Paul, Trueman, Paul, Rod S Taylor, Pavey Toby G, Anokye, Nana, Hillsdon, Melvyn, Taylor Rod S   +26 more
core   +3 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

EDUCATION FOR EXERCISE PROFESSIONALS, DELIVERED BY EXERCISE PROFESSIONALS: THE ACTIVE EDUCATION PROGRAM [PDF]

CASE SETTING Experience as director of a young exercise physiology clinic has facilitated extensive supervision of practicum students and graduates.
Pithers, MN, Sharp, MT
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Feedback Process in The Mini Clinical Evaluation Exercise (Mini-CEX): an Exploratory Study

, 2020
 In the midst of clinical environment unpredictability, feedback helps students to make the most out of clinical learning opportunities. Mini clinical evaluation exercise (Mini-CEX) is considered to be appropriate for providing feedback to students.
Diantha Soemantri; Department of Medical Education Faculty of Medicine Universitas Indonesia Jakarta, Geoff Mccoll; Executive Dean Faculty of Medicine, University of Queensland, Agnes Dodds; Department of Medical Education Melbourne Medical School, University of Melbourne   +2 more
core  

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Revitalizing established teaching and assessment methods in oncological rehabilitation comprehensive laboratory course

Frontiers in Education
In the reform of medical laboratory courses, innovative teaching methods and the development of a teaching assessment system are crucial. However, in past practices, assessments have encountered some issues: a greater emphasis on recording outcomes ...
Yang Li, Yang Li, Xiao-meng Li, Hong Liang, Qian Wei   +4 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Design and implementation of clinical competency evaluation system for nursing students in medical-surgical wards

Journal of Family Medicine and Primary Care, 2019
Background: In nursing, it is important to ensure the evaluation of students' clinical competency and using a valid and reliable evaluation system is necessary.
Forough Rafii, Tahereh Najafi Ghezeljeh, Sepideh Nasrollah   +2 more
doaj   +1 more source