Results 231 to 240 of about 13,357,463 (271)

Identification of small molecule inhibitors of Ebola virus by use of a biologically contained virus system. [PDF]

Virus Res
Amare MG, Halfmann PJ.
europepmc   +1 more source

Chronic Enteropathy Associated With SLCO2A1 Gene Mutation; Initially Misdiagnosed as Fibrostenosing Crohn's Disease. [PDF]

ACG Case Rep J
Gessessew H, Qin D, Sharif N, Gandiga P, Iskandar H.   +4 more
europepmc   +1 more source

Minimal disease activity in Gaucher disease: Criteria for definition

Molecular Genetics and Metabolism, 2012
Gaucher disease type I is a metabolic disorder caused by a genetic deficiency of lysosomal β-glucocerebrosidase that leads to accumulation of glucocerebroside in macrophages, thus causing damage in different organ systems. Enzyme replacement therapy with imiglucerase improves organ impairment and clinical manifestations, but patients differ in response
Maja Di Rocco, Generoso Andria, Bruno Bembi, Francesca Carubbi, GIONA, Fiorina, Gaetano Giuffrida, Silvia Linari, Michelina Sibilio, Vincenzo Spina, Maria Domenica Cappellini   +9 more
core   +4 more sources

Definition of minimal disease activity in psoriasis [PDF]

Journal of the European Academy of Dermatology and Venereology, 2020
AbstractObjectiveTo generate an operational definition to adequately reflect the construct ‘Minimal Disease Activity (MDA)’ in psoriasis.MethodsA systematic review of domains included in clinical trials of psoriasis was presented to a panel of dermatologists and patients. Further domains were elicited by panel discussions.
G. Carretero, J.M. Carrascosa, L. Puig, J.L. Sánchez‐Carazo, A. López‐Ferrer, P. Cueva, C. Soria, R. Rivera, I. Belinchón   +8 more
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Attainment of Minimal Disease Activity Using Methotrexate in Psoriatic Arthritis

The Journal of Rheumatology, 2016
Objective.An international task force has recommended that disease remission or minimal disease activity (MDA) be the target of treatment for psoriatic arthritis (PsA) and that remission or MDA should be attained within 6 months of initiating medication.
Barry J, Sheane, Arane, Thavaneswaran, Dafna D, Gladman, Vinod, Chandran   +3 more
openaire   +2 more sources

Immunotherapy of Minimal Residual Disease by Immunocompetent Lymphocytes and Their Activation by Cytokines

Cancer Investigation, 1992
A murine model of minimal residual disease (MRD) was established utilizing the murine B-cell leukemia (BCL1). BALB/c mice inoculated with up to 10(4) BCL1 were cured (greater than 1 year disease-free survival) following administration of intraperitoneal injections of recombinant human IL-2 (10(5) Cetus units x 3/day intraperitoneally x 5 days ...
S, Slavin, A, Ackerstein, L, Weiss, A, Nagler, R, Or, E, Naparstek   +5 more
openaire   +2 more sources

Minimal disease activity for rheumatoid arthritis: a preliminary definition.

The Journal of rheumatology, 2005
Agreement on response criteria in rheumatoid arthritis (RA) has allowed better standardization and interpretation of clinical trial reports. With recent advances in therapy, the proportion of patients achieving a satisfactory state of minimal disease activity (MDA) is becoming a more important measure with which to compare different treatment ...
Wells, George A., Boers, Maarten, Shea, Beverley, Brooks, Peter M., Simon, Lee S., Strand, C. Vibeke, Aletaha, Daniel, Anderson, Jennifer J., Bombardier, Claire, Dougados, Maxime, Emery, Paul, Felson, David T., Fransen, Jaap, Furst, Dan E., Hazes, Johanna M.W., Johnson, Kent R., Kirwan, John R., Landewé, Robert B.M., Lassere, Marissa N.D., Michaud, Kaleb, Suarez-Almazor, Maria, Silman, Alan J., Smolen, Josef S., Van Der Heijde, Desiree M.F.M., Van Riel, Piet L.C.M., Wolfe, Fred, Tugwell, Peter S.   +26 more
openaire   +7 more sources

Minimal evidence of disease activity (MEDA) in relapsing-remitting multiple sclerosis

Journal of Neurology, Neurosurgery & Psychiatry, 2020
Objective This study aimed to define the minimal evidence of disease activity (MEDA) during treatment that can be tolerated without exposing patients with relapsing-remitting multiple sclerosis at risk of long-term disability. Methods
Prosperini, Luca, Mancinelli, Chiara, Haggiag, Shalom, Cordioli, Cinzia, De Giglio, Laura, De Rossi, Nicola, Galgani, Simonetta, Rasia, Sarah, Ruggieri, Serena, Tortorella, Carla, Pozzilli, Carlo, Gasperini, Claudio   +11 more
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The minimal important difference for measures of urticaria disease activity: Updated findings

Allergy and Asthma Proceedings, 2015
The Urticaria Patient Daily Diary (UPDD) is a validated patient-reported outcome that captures key measures of urticaria disease activity.To update estimates of the minimal important difference (MID) for urticaria disease activity measures in the UPDD, including the weekly itch severity score, weekly number of hives score, weekly average size of ...
Susan D, Mathias, Ross D, Crosby, Karin E, Rosén, James L, Zazzali   +3 more
openaire   +2 more sources