Results 51 to 60 of about 13,357,463 (271)

The efficacy and safety of apremilast in patients with psoriatic arthritis concurrent with comorbidity in clinical practice

Научно-практическая ревматология, 2019
Objective: to evaluate the clinical efficacy and safety of the targeted synthetic disease-modifying antirheumatic drug (DMARD) apremilast (AP; Otesla®) in patients with active psoriatic arthritis (PsA) at 14 and 26 weeks after starting the treatment and ...
E. Yu. Loginova, Yu. L. Korsakova, A. D. Koltakova, E. E. Gubar, P. L. Karpova, S. I. Glukhova, T. V. Korotaeva   +6 more
doaj   +1 more source

Redefining Treat-to-target in Atopic Dermatitis: Towards Meaningful, Patient-centred Disease Control – An ISAD Position Paper

Acta Dermato-Venereologica
Treat-to-target strategies link predefined goals to regular assessment and treatment adaptation. In atopic dermatitis, recent initiatives have mainly defined thresholds using clinician- and patient-reported outcomes.
John Su, Andreas Wollenberg, Melanie Funk, Tina Mesarič, Brandon Hu, Tammi Shipowick, Kelly Barta, Kristin Belleson, Li-Chuen Wong, Kiu Han Kim, Chia-Yu Chu, Sandipan Dhar, Yoshiyuki Kataoka, Kin Fon Leong, Kam Lun Ellis Hon, Erere Otrofanowei, Peter Foley, Lin Ma, Yong Kwang Tay, Marie Lodén, Anousha Yazdabadi, Kathrin A. Gibson, Jonathan D. Akikusa, Andrew Östör, Connie Katelaris, Frank Thien, Michihiro Futamura, Rie Yotsu, Peter Schmid-Grendelmeier, Alain Taïeb   +29 more
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Determination of cytokine profile and fecal calprotectin in patients with inflammatory bowel disease of different activity degree [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2019
Aim: To determine the IL-6, IL-8, TNF-α and fecal calprotectin levels in different phases of the disease and correlate their values with the clinical and endoscopic data in patients with inflammatory bowel diseases.
Ainur Doszhan, Roza Bektayeva, Aiman Galiyeva, Kapura Adrissova   +3 more
doaj   +1 more source

SAT0381 MINIMAL DISEASE ACTIVITY IN PSORIATIC ARTHRITIS PREDICTS LOW IMPACT OF DISEASE [PDF]

Annals of the Rheumatic Diseases, 2019
Background: Psoriatic arthritis (PsA) is the commonest form of inflammatory spondyloarthropathy with prevalence of 0.19% in UK. Patients suffering from PsA often have significant impact on daily life due to articular, non-articular and psychological symptoms.
Ganesh Kasavkar, Siwalik Banerjee, Nicola Gullick   +2 more
openaire   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Defining criteria for disease activity states in systemic juvenile idiopathic arthritis based on the systemic Juvenile Arthritis Disease Activity Score [PDF]

Objective To develop and validate cutoff values in the systemic Juvenile Arthritis Disease Activity Score 10 (sJADAS10) that distinguish the states of inactive disease (ID), minimal disease activity (MiDA), moderate disease activity (MoDA), and high ...
Robasto, Francesca, Silva, Rodrigo M., Shalaby, Radwa H., Consolaro, A., Marrani, Edoardo, Villarreal, Giselle, Lotfy, Hala M., Ozen, S., Costi, Stefania, Kriulin, Ivan, Sztajnbok, Flavio, Al‐Mayouf, Sulaiman M., Abu-Zaid, M., Abu‐Rumeleih, S., Hassan, Waleed, Maggio, Maria C., Minoia, F., Civino, Adele, Montin, Davide, Tarantola, Letizia, Khubchandani, Raju, Fouad, Nermeen A., Osman, Naglaa S., Vilaiyuk, Soamarat, Filocamo, Giovanni, Pal, P., Maldar, Naziya P., Almaaitah, Hiba, Al‐Sofyani, Fuad, Bracaglia, C., El Owaidy, R., El Miedany, Yasser, Alzyoud, Raed, Pardeo, M., Khan, A., Mahgoub, Marwa Y., Patrone, Elisa, Bathia, Jigna N., Saad‐Magalhães, Claudia, Eissa, M., Lerkvaleekul, Butsabong, Simonini, Gabriele, De Benedetti, F., Katsicas, María M., Ravelli, A., Rebollo‐Gimenez, Ana I., Mosa, D., Bayindir, Yagmur, Licciardi, F., Abu‐Shady, Hend, Vyzhga, Y., Radwan, Ahmed R., Alexeeva, Ekaterina, Dvoryakovskaya, Tatyana, Marino, Achille, Nasef, S., Kostik, M., Dāvidsone, Zane, Pistorio, Angela, Adel, Yasmin, Diomeda, Federico, Alsuweiti, Motasem, Rosina, Silvia, Tabra, Samar A. A., Rossano, Martina, El‐Ghoneimy, Dalia H., Mohamed, Sheren E. M., Belozerov, Konstantin E., Abu-Shady, Hend, De Benedetti, Fabrizio, Maggio, Maria C, Maldar, Naziya P, Abu‐Rumeileh, Sarah, Eissa, Mervat, Tabra, Samar A A, Mosa, Doaa M, Mohamed, Sheren E M, Belozerov, Konstantin E, Al-Sofyani, Fuad, Lotfy, Hala M, Abu‐Zaid, Mohamed H., Bathia, Jigna N, Saad-Magalhães, Claudia [UNESP], Rebollo-Giménez, Ana I, Kostik, Mikhail M, Katsicas, María M, El Owaidy, Rasha, Vyzhga, Yulia, Radwan, Ahmed R, Saad-Magalhães, Claudia, Osman, Naglaa S, Ozen, Seza, Abu-Rumeileh, Sarah, Kostik, Mikhail M., El-Ghoneimy, Dalia H, Nasef, Samah I, Pardeo, Manuela, Bracaglia, Claudia, Rebollo-Gimenez, Ana I., Silva, Rodrigo M, Al-Mayouf, Sulaiman M, Khan, Archana, Mosa, Doaa M., Pal, Priyankar, Licciardi, Francesco, Al-Mayouf, Sulaiman M., Consolaro, Alessandro, Abu-Rumeleih, Sarah, Abu-Zaid, Mohamed H., Fouad, Nermeen A, Abu-Zaid, Mohamed H, Shalaby, Radwa H, El-Ghoneimy, Dalia H., Mahgoub, Marwa Y, Nasef, Samah I., Ravelli, Angelo, Minoia, Francesca   +116 more
core   +1 more source

Clinical benefits and complication profile of IL-23 inhibitors in patients with psoriatic arthritis: a systematic review and meta-analysis

Frontiers in Pharmacology
BackgroundPsoriatic arthritis (PsA) is a chronic inflammatory disease with heterogeneous manifestations affecting both joints and skin. Interleukin-23 (IL-23) plays a central role in the Th17-mediated inflammatory pathway implicated in PsA pathogenesis ...
Jingxin Zeng, Ling Lin, Wei Li, Xinjing Gao, Qian Li, Xin Zhou, Weiyu Liu, Xuelian Zhong, Yunqing Yang, Xibao Zhang, Quan Luo   +10 more
doaj   +1 more source

Minimal renal dysfunction in inflammatory bowel disease is related to disease activity but not to 5‐ASA use [PDF]

Alimentary Pharmacology & Therapeutics, 2001
Background:Conflicting data exist about proteinuria in inflammatory bowel diseases. It is still unclear whether the occurrence of proteinuria in inflammatory bowel disease patients is an extra‐intestinal manifestation of disease or the result of adverse effects to medication, especially to aminosalicylates (ASA).Methods:A total of 95 patients (51 with ...
K R, Herrlinger, M K, Noftz, K, Fellermann, K, Schmidt, J, Steinhoff, E F, Stange   +5 more
openaire   +2 more sources