Results 21 to 30 of about 20,895 (206)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Scalar instabilities in bimetric gravity: The Vainshtein mechanism and structure formation
, 2015 We investigate the observational consequences of scalar instabilities in bimetric theory, under the assumption that the Vainshtein mechanism restores general relativity within a certain distance from gravitational sources.
Enander, Jonas, Mortsell, Edvard
core +1 more source
Hadronic Light-Front Wavefunctions and QCD Phenomenology [PDF]
, 2001 A fundamental goal in QCD is to understand the non-perturbative structure of hadrons at the amplitude level--not just the single-particle flavor, momentum, and helicity distributions of the quark constituents, but also the multi-quark, gluonic, and ...
Brodsky, Stanley J.
core +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2010 In deformed or doubly special relativity (DSR) the action of the lorentz group on momentum eigenstates is deformed to preserve a maximal momenta or minimal length, supposed equal to the Planck length.
F. Girelli +22 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Minimal Seesaw as an Ultraviolet Insensitive Cure for the Problems of Anomaly Mediation
, 2007 We show that an intermediate scale supersymmetric left-right seesaw scenario with automatic R-parity conservation can cure the problem of tachyonic slepton masses that arises when supersymmetry is broken by anomaly mediation, while preserving ultraviolet
N. Setzer +4 more
core +2 more sources
Bounds on the permanent and some applications [PDF]
, 2014 We give new lower and upper bounds on the permanent of a doubly stochastic matrix. Combined with previous work, this improves on the deterministic approximation factor for the permanent.
Gurvits, Leonid, Samorodnitsky, Alex
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Orbifold resolutions with general profile
, 2005 A very general class of resolved versions of the C/Z_N, T^2/Z_N and S^1/Z_2 orbifolds is considered and the free theory of 6D chiral fermions studied on it.
Andrea Wulzer +6 more
core +3 more sources