Results 161 to 170 of about 218,683 (273)

Profiling heterologous 3' terminator-dependent expression variation in <i>Aspergillus oryzae</i>. [PDF]

open access: yesSynth Syst Biotechnol
Zhang C   +8 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Zero excess and minimal length in finite coxeter groups

open access: yes
Let \mathcal{W} be the set of strongly real elements of W, a Coxeter group. Then for $w \in \mathcal{W}$, $e(w)$, the excess of w, is defined by $e(w) = \min min \{l(x)+l(y) - l(w)| w = xy; x^2 = y^2 =1}$.
Rowley, P.J., Hart, Sarah B.
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

a multi-objective evolutionary algorithm for minimal visual coverage path problem in raster terrain

open access: yes, 2011
Minimal visual coverage path problem has wide applications, such as selecting the marching route and searching the smuggler's path. Average horizon of a path, which is the ratio of its visual coverage to its length, can be used to measure how covert a ...
Zheng Chang Wen, Li Jie, Hu Xiaohui
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji   +13 more
wiley   +1 more source

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