Results 121 to 130 of about 1,734,778 (295)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Animals, 2019 Pregnancy and lactation are challenging states that affect maternal and lamb health. In Lacaune dairy sheep, we evaluated the impact of parity, pregnancy rank, and body condition on body weight and the condition of ewes and lambs in mid-pregnancy (75 ...
Jose Luis Pesántez-Pacheco +13 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Minimal anisotropic groups of higher real rank [PDF]
, 2010 The purpose of this thesis is to give a classification of anisotropic algebraic groups over number fields of higher real rank. This will complete the classification of algebraic groups over number fields of higher real rank, which was begun by V ...
Ondrus, Alexander A.
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
On Redei matrices with minimal rank [PDF]
The 4-rank of the narrow ideal class groups of quadratic number fields can be computed from the rank of certain f0, 1g-matrices defined by Redei. A lower bound of the rank of Redei's matrices was also given by Redei.
Sueyoshi, Yutaka
core
A Theoretical Study on the Rank of the Integral Operators for Large-‐Scale Electrodynamic Analysis [PDF]
, 2011 We theoretically prove that the minimal rank of the interaction between two separated geometry blocks in an integral-equation based analysis of general three-dimensional objects, for a prescribed error bound, scales linearly with the electric size of the
Chai, Wenwen, Jiao, Dan
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
APPLICATION OF RANKING BASED ATTRIBUTE SELECTION FILTERS TO PERFORM AUTOMATED EVALUATION OF DESCRIPTIVE ANSWERS THROUGH SEQUENTIAL MINIMAL OPTIMIZATION MODELS [PDF]
ICTACT Journal on Soft Computing, 2014 In this paper, we study the performance of various models for automated evaluation of descriptive answers by using rank based feature selection filters for dimensionality reduction.
C. Sunil Kumar, R.J. Rama Sree
doaj